This study is testing a new way to help people quit smoking using a device called low intensity focused ultrasound (LIFU). LIFU aims to target specific areas deep in the brain linked to nicotine addiction. You would receive either active LIFU treatments or sham (inactive) LIFU treatments, two times a week for four weeks. Researchers will measure how many cigarettes you smoke per day and look at your brain activity using fMRI (functional magnetic resonance imaging) scans to see if the treatment is successful. To join, you need to be between 20 and 60 years old, have smoked for at least five years, and meet other health requirements. The study plans to enroll 100 participants, but its current status is unclear.

Study design

This is an interventional study, meaning participants will receive a specific treatment. It plans to enroll 100 participants, but the phase of the study is not specified.

What's involved

You would receive two LIFU sessions a week for four weeks. You will also have assessments at baseline, after session 1, after session 8, and at a one-week follow-up, which includes fMRI scans.

Compensation

Not stated in the trial record.

Follow-up

Participants will have a one-week follow-up appointment about five weeks after starting the study.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.