Lavender Aromatherapy for Anxiety and Pain During Awake Procedures

This study is looking at whether lavender aromatherapy can help reduce anxiety and pain for adults having awake ear, nose, and throat (otolaryngologic) procedures in a clinic. You might be eligible if you are at least 18 years old and are having one of these procedures, such as for Inferior Turbinate Hypertrophy (enlarged nasal tissues) or Chronic Rhinosinusitis (long-term sinus inflammation). Researchers will compare lavender essential oil to a placebo (an odorless liquid) to see if lavender aromatherapy makes you more comfortable. The main goal is to see if lavender aromatherapy reduces anxiety and pain, measured by scales, and if patients find it relaxing. The study plans to enroll 184 participants.

Study design
This is an interventional study comparing lavender aromatherapy to a placebo. It plans to enroll 184 adult participants.
What's involved
You will have your scheduled procedure with either lavender aromatherapy or placebo. You will also take a short survey.
Compensation
Not stated in the trial record.
Follow-up
Anxiety and pain will be measured at baseline, during the procedure, and immediately after the procedure.

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NCT07299474

Efficacy of Lavender Aromatherapy on Anxiety and Pain Reduction During Awake Otolaryngologic Procedures

Recruiting
NAAges 18+InterventionalTreatment
Cedars-Sinai Medical Center
~184 participants
Updated 2025-12-23 on ClinicalTrials.gov
What's tested:Lavender AromatherapyPlacebo Aromatherapy

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in visual analog scale anxiety, measured on a 10 cm scale
Measured over Baseline, Periprocedural and Immediately after the procedure
+2 more outcomes measured
Inferior Turbinate Hypertrophy
Chronic Rhinosinusitis (CRS)
Rhinitis, Vasomotor
Thyroid Nodules
Vocal Fold Immobility
1 sites across 1 states
California1
  • Ankona Ghosh, MD · PRINCIPAL_INVESTIGATOR · Cedars-Sinai Medical Center

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Eligibility criteria

Inclusion

Adults ≥18 years old undergoing awake otolaryngologic procedures in the outpatient clinic
Able to provide informed consent

Exclusion

Hypersensitivity to fragrances
Taking systemic NSAIDs or other systemic pain-relieving medications within 48 hours
Taking anxiolytics, hypnotics, sedating antihistamines, antidepressants on regular basis within 4 weeks
Pregnant or breastfeeding
Participation in another clinical research study within the prior 30 days
  • Change in visual analog scale anxiety, measured on a 10 cm scaleBaseline, Periprocedural and Immediately after the procedure

    A 10 cm visual analog scale is widely utilized to measure procedural anxiety, rated from 0 to 10, with 10 being the highest level of anxiety. The patient will provide a vertical mark above their level of anxiety. This number measured in mm (0-100) will be recorded both immediately before the procedure, and after the procedure, where the patient will record their average level of anxiety during the procedure. The change between pre-procedure, and post-procedure, will be recorded for each patient and compared between the lavender aromatherapy and placebo groups. The mean and median pre-procedure and post-procedure values will also be compared between the groups.

  • Likert scale of pain, measured on a scale of 0-10Immediately after the procedure

    Patients will be asked to rate their your average level of pain on a scale of 0 (no pain) to 10 (worst possible pain) on a post-procedural questionnaire

  • Likert scale subjective improvement with pain, measured on scale of 1-5Immediately after the procedure

    Patients will be asked in post-procedural questionnaire if they felt the aromatherapy helped with pain during the procedure, on a scale of 1 (strongly disagree) to 5 (strongly agree)