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NCT07301125

Myofunctional Therapy for Obstructive Sleep Apnea

Enrolling by Invitation
NAAges 18–65InterventionalBasic science
University of Minnesota
~30 participants
Updated 2026-07-30 on ClinicalTrials.gov
What's tested:Myofunctional Therapy

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
MFT treatment fidelity
Measured over Day 90
+1 more outcome measured

Conditions

Obstructive Sleep Apnea

Explore related trials

Obstructive Sleep Apnea

Where it's being run

1 sites across 1 states
Minnesota1

Study leadership

  • Jesse Hoffmeister, PhD, CCC-SLP · PRINCIPAL_INVESTIGATOR · University of Minnesota

Who to contact

This trial hasn't published a contact. View it on ClinicalTrials.gov

Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Adults aged 18-65
New diagnosis of OSA (AHI ≥ 5) or failure of first-line OSA treatment
Willingness to forego first-line OSA treatment or stop current OSA treatment for 3 months

Exclusion

Medical comorbidities that require restricting fluid intake (e.g., dysphagia, renal disease, liver disease, hyponatremia)
Severe nasal obstruction
Severe ankyloglossia
Craniofacial abnormality
Severe pulmonary disease
Severe post-traumatic stress disorder (PCL-5 \> 33)
Very severe insomnia (ISI \> 22)
Body mass index (BMI) ≥30 kg/m2.
History of TBI
Known oropharyngeal or esophageal dysphagia
Pregnancy
Allergy to topical anesthetic
Inability to fast for 6 hours
Recent facial trauma
Recent nasal, pharyngeal, laryngeal, or esophageal surgery
Known nasal, pharyngeal or esophageal obstruction
Current upper respiratory infection
Insufficient internet/computer access to participate in remote study visit
Severe excessive daytime sleepiness (risk of motor vehicle accidents)
Heart failure, recent stroke, heart attack, etc.
Nasal Obstruction Symptom Evaluation (NOSE) Scale \>15

What this trial measures

  • MFT treatment fidelityDay 90

    Treatment fidelity of two common MFTs (high-intensity swallowing exercises, respiratory muscle strength training) in individuals with OSA. Treatment fidelity will be determined via measuring the percent of sessions completed relative to the targeted number of sessions.

  • Pressure generation in posterior upper airway musculatureDay 90

    Comparison of pressure generation in posterior upper airway musculature before and after MFT intervention as assessed with HRM