Observational Study for Hepatocellular Carcinoma After Y90
This study is looking at people with hepatocellular carcinoma (HCC), a type of liver cancer, who are receiving Y90 radioembolization treatment. Researchers want to see if they can use "liquid biopsies" (blood tests that look for cancer cells or DNA in your blood) to predict how well you will respond to Y90 treatment. They will collect blood samples at different times to look for circulating tumor cells (CTCs) and cell-free DNA (cf-DNA) from your cancer. This study aims to understand if these blood tests, along with imaging, can help predict treatment success. You may be able to join if you are at least 18 years old, have HCC, and your doctors have approved you for Y90 treatment.
- Study design
- This is an observational study with a planned enrollment of 12 participants. It is not a randomized trial, meaning participants are not assigned to different treatment groups.
- What's involved
- You would have blood samples taken at the start of the study, and then again 1 month, 3 months, and 6 months after your Y90 treatment. You would also have CTA imaging scans at the start, 3 months, and 6 months after treatment.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for at least 6 months after their Y90 treatment, with assessments at 1, 3, and 6 months.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Liquid Biopsy for Hepatocellular Carcinoma Molecular Characterization After Y90
At a glance
Conditions
NCT07303712
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
VA Palo Alto Health Care System
Palo Alto, Californiastudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Sirish Kishore, MD · PRINCIPAL_INVESTIGATOR · VA Palo Alto Health Care System
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Circulating Tumor Cell (CTC)Baseline, 1 month post treatment, 3 months post treatment, and 6 months post treatment
blood samples
- CTA imagingBaseline, 3 months post treatment, 6 months post treatment
imaging of liver tumor