A Phase 2A Trial of DT402 for Autism Spectrum Disorder
{ "Phase 2A Trial of DT402 for Autism Spectrum Disorder", "This study is testing a drug called DT402 in adults with Autism Spectrum Disorder (ASD). DT402 is a psychoactive substance that affects brain chemicals like serotonin. The study aims to see how DT402 changes your symptoms related to socialization and communication. You might be able to join if you are an adult between 18 and 65 years old with an ASD diagnosis and significant challenges in social interaction and communication. The main way they will measure if the treatment is working is by looking at changes in your pain or symptom scores over time. The current status of this study is unclear, but it plans to enroll about 20 people.", "design": "This is an open-label study, meaning you and the researchers will know if you are receiving the study drug. It is a single-center study and plans to enroll about 20 adults.", "commitments": "You would receive a single dose of DT402. Your symptom scores will be measured at several points: before the dose, at 2, 4, 6, 8, and 24 hours after the dose, and again on day 15.", "compensation": "Not stated in the trial record.", "follow_up": "Your symptoms will be monitored up to 15 days after receiving the dose of DT402.", }
- Study design
- Not specified.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- Not specified.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
A Phase 2A Trial of DT402 for Autism Spectrum Disorder
At a glance
Conditions
NCT07303907
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Spectrum Neuroscience and Treatment Institute
New York, New Yorkstudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Change from Baseline in 11-point Numerical Rating Scale (NRS) scoresBaseline, pre-dose and 2, 4, 6, 8, and 24 hours post-dose and day 15
The NRS is an 11-point PRO scale used to measure the severity or intensity of effects from 0 (no effect) to 10 (high severity or intensity of effect). It consists of various items related to both positive and negative effects in the autism patient population.