Probiotics for Rheumatoid Arthritis

This study is looking at whether a probiotic called Align Extra Strength Probiotic Supplement (which contains 5 billion live bacteria per capsule) can affect people with rheumatoid arthritis (RA). Researchers want to see if this probiotic can successfully colonize (grow and live) in your gut. You might be able to join if you are 18 or older, have had RA for more than 6 months, and have been on stable RA treatment for at least 3 months. The study plans to enroll 50 participants. The current status of the study is unclear.

Study design
This is an interventional study, meaning participants will receive a specific treatment. It plans to enroll 50 participants.
What's involved
You would take the probiotic daily for 6 weeks. You will collect stool samples every other day for the first 3 weeks and twice weekly for the last 3 weeks. You will also have clinic visits at the beginning, at week 3, and at week 6.
Compensation
Not stated in the trial record.
Follow-up
The primary outcome, probiotic bacterial colonization, is measured at 6 weeks.

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NCT07304505

Probiotics in Adults With Rheumatoid Arthritis

Recruiting
NAAges 18+Interventional
Ancilia Biosciences
~50 participants
Updated 2025-12-31 on ClinicalTrials.gov
What's tested:Align Extra Strength Probiotic Supplement

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Probiotic bacterial colonization
Measured over 6 weeks
Rheumatoid Arthritis (RA)
1 sites across 1 states
Illinois1

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  • Probiotic bacterial colonization6 weeks

    Change from baseline (Day 0) to Day 39 (including intermediate time points) in the relative abundance and/or detection frequency of the administered probiotic strain in stool