Back to search results

On-Trac: Online Intervention for Cancer Survivors Managing Anxiety

This study is testing an online program called On-Trac (Online Training After Cancer) for adult cancer survivors who are experiencing anxiety. On-Trac uses strategies from Cognitive-Behavioral Therapy (CBT) and Acceptance Commitment Therapy (ACT) to help manage anxiety. You might be able to join if you are at least 18 years old, had a cancer diagnosis (not including non-melanoma skin cancer) at least 12 months ago, and have not had active cancer therapy in the past 4 months. The study will measure how much your anxiety changes after using On-Trac. The current status of this study is unclear, but it plans to enroll about 80 people.

Study design
This is an interventional study designed to refine the On-Trac program. It plans to enroll about 80 participants, grouped into four age-based cohorts.
What's involved
You would complete an online survey, participate in a 120-minute online group session, and have 1-2 individual coaching sessions. You would also complete follow-up questionnaires and a telephone interview at 4 and 8 weeks.
Compensation
Participants will receive gift card incentives for completing evaluations and follow-up questionnaires/interviews, with a maximum total of $90.
Follow-up
Participants will be followed for 8 weeks after the group education session, with assessments at 4 and 8 weeks.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07305740

On-Trac: An Online Intervention for Cancer Survivors Managing Anxiety

Recruiting
NAAges 18+InterventionalSupportive care
Dana-Farber Cancer Institute
~80 participants
Updated 2026-05-13 on ClinicalTrials.gov
What's tested:ON-TRAC Education sessionON-TRAC Coaching

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in OASIS (Overall Anxiety Severity and Impairment Scale) from baseline to 4 weeks
Measured over Anxiety measures will be collected once at baseline prior to receiving On-Trac intervention, and at follow-up 4 and 8 weeks post-baseline.
+9 more outcomes measured

Conditions

Cancer
Survivorship
Anxiety

Explore related trials

AnxietyCancer SurvivorshipMalignant Neoplasm

Where it's being run

1 sites across 1 states
Massachusetts1

Study leadership

  • Christopher J Recklitis, PhD, MPH · PRINCIPAL_INVESTIGATOR · Dana-Farber Cancer Institute

Who to contact

On-Trac Study Coordinator
[email protected]
617-582-8260
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

Age ≥ 18
A diagnosis of cancer (except non-melanoma skin cancer) ≥ 12 months prior.
No active cancer therapy (excluding chemoprevention) in the past 4 months, and no further therapy planned.
Significant anxiety as evidenced by both of the following
Endorsement of the SCID ( Structured Clinical Interview for the DSM-5) Screener Items for Social Anxiety Disorder, Generalized Anxiety Disorder, Agoraphobia, Specific Phobia, or Illness Anxiety Disorder.
A score ≥ 6 on the Overall Anxiety Severity and Impairment Scale (OASIS).
Regular access to the internet.
Ability to read and write in English.

Exclusion

Significant symptoms of Panic Disorder in the prior month, including anticipatory anxiety of having a future panic attack or avoidance symptoms associated with panic attacks, as assessed by three SCID-5 items from the panic attack disorder module.
Significant symptoms of Obsessive Compulsive Disorder, as evidenced by any obsessions over the past 3 months, as assessed by three SCID items from the Obsessive Compulsive Disorder module.
Psychiatric hospitalizations or emergency room visits for psychiatric care in the prior 2 years.
In the next two months, intention to use or likelihood of using emergent or "rescue" anxiety medication (e.g., Ativan, Xanax, Valium) or self-prescribed substances (i.e., marijuana) at the onset of anxiety symptoms or when entering a situation where they expect to experience anxiety.
Any significant marijuana use which could impact anxiety symptoms, as evidenced by one of the following:
4 days of marijuana use in any week in the last month
20 milligrams of THC (Tetrahydrocannabinol) products in any week in the last month.
Participation in any CBT or ACT-based behavioral or education intervention for anxiety in the past 2 years. This includes in-person, asynchronous, and synchronous online anxiety programs, and therapy that includes these skills. This does not include independent use of any self-help materials (i.e., workbooks, books).
Any impairment (e.g., hearing, visual, cognitive) that interferes with the ability to complete all parts of the study independently.

What this trial measures

  • Change in OASIS (Overall Anxiety Severity and Impairment Scale) from baseline to 4 weeksAnxiety measures will be collected once at baseline prior to receiving On-Trac intervention, and at follow-up 4 and 8 weeks post-baseline.

    OASIS is a 5-item self-report measure, where the total score is obtained as a sum of the individual items. Higher scores are indicative of more severe and impairing anxiety symptoms.

  • Change in OASIS (Overall Anxiety Severity and Impairment Scale) from baseline to 8 weeksAnxiety measures will be collected once at baseline prior to receiving On-Trac intervention, and at follow-up 4 and 8 weeks post-baseline.

    OASIS is a 5-item self-report measure, where the total score is obtained as a sum of the individual items. Higher scores are indicative of more severe and impairing anxiety symptoms.

  • Change in AAQ-2 (Acceptance and Action Questionnaire - Version 2) from baseline to 4 weeksAnxiety measures will be collected once at baseline prior to receiving On-Trac intervention, and at follow-up 4 and 8 weeks post-baseline.

    AAQ-2 is a 7-item self report measure, where the total score is obtained as a sum of the individual items. Higher scores are indicative of higher psychological inflexibility.

  • Change in AAQ-2 (Acceptance and Action Questionnaire - Version 2) from baseline to 8 weeksAnxiety measures will be collected once at baseline prior to receiving On-Trac intervention, and at follow-up 4 and 8 weeks post-baseline.

    AAQ-2 is a 7-item self report measure, where the total score is obtained as a sum of the individual items. Higher scores are indicative of higher psychological inflexibility.

  • Change in PROMIS-Anxiety from baseline to 4 weeksAnxiety measures will be collected once at baseline prior to receiving On-Trac intervention, and at follow-up 4 and 8 weeks post-baseline.

    PROMIS-Anxiety is a 7-item self report measure, where the total score is obtained as a sum of the individual items. Higher scores are indicative of greater severity of anxiety symptoms.

  • Change in PROMIS-Anxiety Short Form 7a (SF-7a) from baseline to 8 weeksAnxiety measures will be collected once at baseline prior to receiving On-Trac intervention, and at follow-up 4 and 8 weeks post-baseline.

    PROMIS-Anxiety SF-7 is a 7-item self report measure, where the total score is obtained as a sum of the individual items. Higher scores are indicative of greater severity of anxiety symptoms.

  • Change in IAQ (Illness Anxiety Questionnaire) from baseline to 4 weeksAnxiety measures will be collected once at baseline prior to receiving On-Trac intervention, and at follow-up 4 and 8 weeks post-baseline.

    IAQ is a 7-item self report measure, with all items adapted from the Short Health Anxiety Inventory (SHAI). The total score is obtained as a sum of the individual items.

  • Change in IAQ ( Illness Anxiety Questionnaire) from baseline to 8 weeksAnxiety measures will be collected once at baseline prior to receiving On-Trac intervention, and at follow-up 4 and 8 weeks post-baseline.

    IAQ is a 7-item self report measure, with all items adapted from the Short Health Anxiety Inventory (SHAI). The total score is obtained as a sum of the individual items.

  • Change in PROMIS-Self Efficacy from baseline to 4 weeksAnxiety measures will be collected once at baseline prior to receiving On-Trac intervention, and at follow-up 4 and 8 weeks post-baseline.

    SIx PROMIS-Self Efficacy items were selected from the PROMIS item bank for managing chronic conditions - managing emotions. A total score is obtained as a sum of the individual items. Higher scores are indicative of greater self-efficacy for managing emotions.

  • Change in PROMIS-Self Efficacy from baseline to 8 weeksAnxiety measures will be collected once at baseline prior to receiving On-Trac intervention, and at follow-up 4 and 8 weeks post-baseline.

    Six PROMIS-Self Efficacy items were selected from the PROMIS item bank for managing chronic conditions - managing emotions. A total score is obtained as a sum of the individual items. Higher scores are indicative of greater self-efficacy for managing emotions.