Methylphenidate and Response to Alcohol Cues Study
This study is looking at whether a single dose of methylphenidate (also known as Ritalin), a medication that can improve attention, affects how people with Alcohol Use Disorder (AUD) respond to alcohol cues. Researchers want to see if improving attention can reduce cravings and brain responses to alcohol-related sights and sounds. You might be able to join if you are 18-25 years old, have AUD, speak English, and have normal or corrected vision. The study will measure brain activity and cravings 15 minutes after you take either methylphenidate or a placebo (an inactive pill). The study plans to enroll 50 participants, but its current recruitment status is unclear.
- Study design
- This interventional study plans to enroll 50 participants. It will compare the effects of methylphenidate to a placebo.
- What's involved
- You would participate in one remote session and two in-person sessions. These sessions will involve fMRI (a type of brain scan) and behavioral testing.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary outcome, neural responses to cues, is measured at 15 minutes.
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Methylphenidate and Response to Alcohol Cues
At a glance
Conditions
Where it's being run
1 sites across 1 statesWho to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Neural responses to cues15 minutes
Whole-brain cue-elicited fMRI responses will be examined by contrasting activation following alcohol images with brain activation following neutral images. Regions-of-interest analysis will focus on anterior cingulate cortex, dorsal striatum, ventral striatum, and amygdala.