Virtual Reality Cognitive Training for Brain Cancer Survivors
This study is looking at whether a virtual reality (VR) training program can help brain cancer survivors who have finished their treatment. The VR program, called VR-CRT, uses games to try and improve thinking skills (cognitive function), well-being, mental health, and quality of life. Some participants will use the VR system, while others will do word search puzzles. The study wants to see if at least 80% of participants can complete the VR program over 4 weeks, and if they find it acceptable. It also measures changes in thinking skills. You might be able to join if you are an adult (18 or older) who has survived a low-grade glioma (a type of brain cancer), have mild cognitive impairment (MCI), and finished all your cancer treatments between 30 days and 24 months ago. The study aims to enroll 40 participants, but its current recruitment status is unclear.
- Study design
- This is an interventional study planning to enroll 40 participants. Participants will be randomized to either use a Virtual Reality System or complete Word Search Puzzles.
- What's involved
- Participants will use either the VR system or word search puzzles for 4 weeks. Thinking skills will be measured at the beginning and after the 4-week intervention.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for 4 weeks, with measurements taken at the end of this period.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Measuring the Feasibility and Effect of a Virtual Reality Cognitive Training Intervention for Brain Cancer Survivors.
At a glance
Conditions
NCT07313709
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
University of Cincinnati Medical Center
Cincinnati, Ohiostudy coordinator listed
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Who to contact
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Exclusion
What this trial measures
- Feasibility defined as >80% (> 16 participants out of 20) able to complete the experimental arm study in 4 weeks.4 weeks
FEASIBILITY: Measure the feasibility of using VR-CRT and Control (i.e., paper-based Word-search puzzles (WSP)) with brain cancer survivors (BCS) experiencing cancer-related cognitive impairment (CRCI). Feasibility: will be defined as \>80% (\> 16 participants out of 20) able to complete the experimental arm study in 4 weeks. Since the standard/control arm is well established and routine, feasibility evaluation is not required in this arm. (If subjects withdraw in disproportion in two arms after the randomization, the study may be suspended for further evaluation.)
- Acceptability defined as scores of >8 on each subscale of the Senior Technology Acceptance Model (STAM).54 The STAM (Short Version) measures four attitudes towards technology on a Likert scale of 1-10.4 weeks
ACCEPTABILITY: Measure the acceptability of using VR-CRT and Control (i.e., paper-based Word-search puzzles (WSP)) with brain cancer survivors (BCS) experiencing cancer-related cognitive impairment (CRCI). Acceptability: will be defined as scores of \>8 on each subscale of the Senior Technology Acceptance Model (STAM).54 The STAM (Short Version) measures four attitudes towards technology on a Likert scale of 1-10. (See sections 3.1, 17.1 for detail.) This score of \>8 for all 14 responses will be calculated as an average of all of the completed sub-scales per each subject. Any missing sub-scales (non-response by subjects) will not be considered into the calculation of the mean per subject. The score of \>8 must be observed in \>80% (\>32 participants) to be considered acceptable.
- Effect of VR-CRT (and Control) on cognitive function measured by scores at baseline and post-intervention,using 1.) Hopkins Verbal Learning Test4 weeks
EFFECT: Estimate the effect of VR-CRT (and Control) on brain cancer survivors' cognitive function such as memory, attention/focus, processing speed, and executive function. Effect: will be measured by 1.) Hopkins Verbal Learning Test (HVLT)
- Effect of VR-CRT (and Control) on cognitive function measured by scores at baseline and post-intervention,using 2.) Controlled Oral Word Association4 weeks
EFFECT: Estimate the effect of VR-CRT (and Control) on brain cancer survivors' cognitive function such as memory, attention/focus, processing speed, and executive function. Effect: will be measured by comparing scores collected at baseline and post-intervention, (i.e., at the conclusion of a four-week intervention period) using 2.) Controlled Oral Word Association (COWA)
- Effect of VR-CRT (and Control) on cognitive function measured by scores at baseline and post-intervention,using 3.) Trail Making A-B4 weeks
EFFECT: Estimate the effect of VR-CRT (and Control) on brain cancer survivors' cognitive function such as memory, attention/focus, processing speed, and executive function. Effect: will be measured by comparing scores collected at baseline and post-intervention, (i.e., at the conclusion of a four-week intervention period) using 3.) Trail Making A-B (TMa/b).