The CAT-RA Study for Rheumatoid Arthritis and Heart Disease Risk

This study, called CAT-RA, is looking at how to better identify people with rheumatoid arthritis (RA) who are at higher risk for heart disease. People with RA have a greater chance of having a heart attack. Researchers are testing if measuring high sensitivity cardiac troponin (a blood test for heart damage) and coronary artery calcium (a measure of plaque in heart arteries) can help doctors find these risks earlier. This could lead to starting preventative treatments sooner. You might be able to join if you have RA, are between 35 and 79 years old, and have at least one heart disease risk factor like prediabetes or high blood pressure. The study is looking for 120 participants.

Study design
This is an observational study, meaning participants are observed without receiving a specific treatment from the study. It plans to enroll 120 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint, coronary artery calcium score, is measured at baseline, but no further follow-up is specified.

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NCT07315997

The Coronary Artery Calcium and Troponins in Rheumatoid Arthritis (CAT-RA) Study

Recruiting
Not specifiedAges 35–79Observational
Brigham and Women's Hospital
~120 participants
Updated 2026-07-14 on ClinicalTrials.gov
What's tested:high sensitivity cardiac troponin

At a glance

Recruiting sites
3 of 3 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
coronary artery calcium score
Measured over Cross-sectional, at baseline
Rheumatoid Arthritis (RA
Atherosclerotic Cardiovascular Disease (ASCVD)
3 sites across 1 states
Massachusetts3

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Eligibility criteria

Inclusion

RA diagnosed by a rheumatologist
Age 40- 79
≥1 ASCVD risk factor including prediabetes, hypertension, BMI \>30, current or history of cigarette smoking

Exclusion

Patients on a statin or with a contraindication to statin, on a cholesterol absorption inhibitor, or on a PCSK9 inhibitor
Patients with diabetes mellitus
Pregnancy
  • coronary artery calcium scoreCross-sectional, at baseline

    Quantified coronary artery calcium score