Postoperative Pain Management for Hip Replacement Surgery

This study is looking at ways to manage pain after total hip replacement surgery. Researchers are comparing two approaches for a nerve block (suprainguinal fascia iliaca block) given before surgery. One group will receive ropivacaine, a numbing medicine, alone. The other group will receive ropivacaine combined with dexmedetomidine, a medication that may help the numbing effect last longer. The main goal is to see if adding dexmedetomidine helps patients wait longer before needing their first pain medicine after surgery. You may be able to join if you are between 18 and 80 years old and are having elective total hip replacement surgery. The study status is currently unclear, and it plans to enroll 120 participants.

Study design
This interventional study plans to enroll 120 participants to compare two different treatments for pain management after hip surgery. Participants will receive either ropivacaine alone or ropivacaine combined with dexmedetomidine.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The time to first analgesic request will be assessed for up to 24 hours after the block administration.

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NCT07316166

Suprainguinal Fascia Iliaca Block With vs Without Dexmedetomidine

Recruiting
PHASE4Ages 18–80InterventionalSupportive care
Rhode Island Hospital
~120 participants
Updated 2026-03-25 on ClinicalTrials.gov
What's tested:DexmedetomidineRopivacaine

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Time of administration of first analgesic after the surgery
Measured over Time to first analgesic request, defined as the interval (in minutes) from block administration to the first request for rescue analgesia, assessed for up to 24 hours.
Postoperative Pain Management
1 sites across 1 states
Rhode Island1

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Eligibility criteria

Inclusion

Patients undergoing elective total hip arthroplasty
18-80 years old
ASA 1-3 classifications

Exclusion

ASA classification of 4 or greater
Infection at the site of nerve blockade
Coagulopathy
Known allergy to study medications
Chronic opioid consumption (\>3 months)
Currently using lidocaine patches
Pre-existing neuropathy
A history of CVA
High grade atrioventricular block (cardiac conduction system impairment)
Organ dysfunction (cardiac failure, respiratory failure, end stage renal disease, hepatic dysfunction, hypoalbuminemia)
Morbid obesity (≥40 kg/m2)
Prior surgery in supra and/or infrainguinal region
Non-English-speaking participants
  • Time of administration of first analgesic after the surgeryTime to first analgesic request, defined as the interval (in minutes) from block administration to the first request for rescue analgesia, assessed for up to 24 hours.