Study of REGN13335 for Pulmonary Arterial Hypertension (PAH)

This study is testing an experimental drug called REGN13335 for adults with Pulmonary Arterial Hypertension (PAH), a condition where blood pressure in the arteries of the lungs is too high. The goal is to see how safe and effective REGN13335 is when taken with your current PAH medications. Researchers will also look at potential side effects and how your body processes REGN13335. You may be able to join if you have a documented diagnosis of PAH, are in WHO functional class II or III, and are on a stable dose of other PAH treatments. The main way success will be measured is by looking at changes in your Pulmonary Vascular Resistance (PVR) after 24 weeks. The current recruitment status is unclear.

Study design
This interventional study plans to enroll 99 participants and will compare REGN13335 to a placebo (an inactive substance).
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint is measured at week 24, indicating follow-up for at least that duration.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07318597

Study of REGN13335 in Adult Participants With Pulmonary Arterial Hypertension (PAH)

Recruiting
PHASE2Ages 18+InterventionalTreatment
Regeneron Pharmaceuticals
~99 participants
Updated 2026-09-15 on ClinicalTrials.gov
What's tested:REGN13335Placebo

At a glance

Recruiting sites
30 of 30 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change from baseline in Pulmonary Vascular Resistance (PVR)
Measured over At week 24
Pulmonary Arterial Hypertension (PAH)

NCT07318597

Where you'd take part

This study runs at 30 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Asan Medical Center

    Seoul, Songpa-gu, South Koreano site contact published

    Recruiting

  • Clinic of University Greifswald

    Greifswald, Germanyno site contact published

    Recruiting

  • Gachon University Gil Medical Center

    Namdong-gu, Incheon, South Koreano site contact published

    Recruiting

  • H.U.B. Erasme Hospital

    Brussels, Belgiumno site contact published

    Recruiting

  • Hopital Bicetre

    Le Kremlin-Bicêtre, Franceno site contact published

    Recruiting

  • Hospital Clinic, Barcelona

    Barcelona, Spainno site contact published

    Recruiting

  • Hospital Universitario Costa del Sol

    Marbella, Malaga, Spainno site contact published

    Recruiting

  • Hospital Universitario De Toledo

    Toledo, Spainno site contact published

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Clinical Trial Management · STUDY_DIRECTOR · Regeneron Pharmaceuticals

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  • Change from baseline in Pulmonary Vascular Resistance (PVR)At week 24