Kaempferol Absorption and Pharmacokinetics Evaluation
This study is looking at how your body absorbs and uses Kaempferol, a natural compound found in many plants. We want to understand how much Kaempferol gets into your system and how long it stays there. You would take Kaempferol capsules once a day for 8 days. We'll collect blood and urine samples to measure Kaempferol levels and check for any changes in your body. This study is for healthy adults aged 18 to 70. We aim to enroll 120 participants. The study's status is currently unclear, so we don't know if it's actively recruiting yet.
- Study design
- This is an interventional study involving 120 healthy adult participants. It is designed to evaluate how the body absorbs and processes Kaempferol.
- What's involved
- You would take Kaempferol orally once daily for 8 days. This involves clinic visits, blood draws, urine collection, and follow-up assessments.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your Kaempferol levels will be measured from the first dose through 24 hours after your final dose on Day 8.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Kaempferol Absorption and Pharmacokinetics Evaluation
At a glance
Conditions
NCT07322406
Where you'd take part
This study runs at 3 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
University of North Carolina at Chapel Hill
Chapel Hill, North Carolinastudy coordinator listed
Not yet recruiting
University of Pittsburgh
Pittsburgh, Pennsylvaniastudy coordinator listed
Recruiting
Weill Cornell Medicine
New York, New Yorkstudy coordinator listed
Not yet recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Afshin Beheshti, PhD · PRINCIPAL_INVESTIGATOR · University of Pittsburgh
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
Want this trial checked against your situation?
Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.
Inclusion
Exclusion
What this trial measures
- Maximum plasma concentration (Cmax) of KaempferolFrom dosing on Day 1 through 24 hours after the final dose (Day 8)
The maximum observed plasma concentration of Kaempferol following oral administration, calculated from serial plasma samples collected at predefined time points.
- Time to maximum plasma concentration (Tmax) of KaempferolFrom dosing on Day 1 through 24 hours after the final dose (Day 8)
The time elapsed from oral administration of Kaempferol to the occurrence of the maximum observed plasma concentration (Cmax), determined from serial plasma sampling.
- Area under the plasma concentration-time curve (AUC) of KaempferolFrom dosing on Day 1 through 24 hours after the final dose (Day 8)
The area under the plasma concentration-time curve of Kaempferol, calculated using noncompartmental methods to quantify overall systemic exposure following oral administration.
- Plasma elimination half-life (t½) of KaempferolFrom dosing on Day 1 through 24 hours after the final dose (Day 8)
The terminal elimination half-life of Kaempferol in plasma, estimated from the terminal phase of the concentration-time curve following oral administration.
- Apparent clearance of KaempferolFrom dosing on Day 1 through 24 hours after the final dose (Day 8)
The apparent systemic clearance of Kaempferol following oral administration, calculated using standard pharmacokinetic methods based on plasma concentration data.
- Urinary excretion of Kaempferol and metabolitesFrom dosing on Day 1 through 24 hours after the final dose (Day 8)
The cumulative amount of Kaempferol and its metabolites excreted in urine, determined from timed urine collections following oral administration.