This study is looking at how combining exoskeleton-assisted walking (EAW) with transcutaneous spinal cord stimulation (tSCS) affects bone and muscle health in people with long-term spinal cord injury (SCI). The study aims to see if this combination can help improve bone strength and muscle size, which are often lost after SCI. You could be eligible if you are between 21 and 60 years old and have a spinal cord injury. The study will compare participants who receive full tSCS with those who receive a very low, inactive (sham) tSCS, both while using an exoskeleton. The main way they will measure success is by looking at the muscle size in your mid-thigh after 9 months. The study plans to enroll 24 participants, but its current status is unclear.

Study design

This is an interventional study comparing two groups: one receiving active transcutaneous spinal cord stimulation (tSCS) and the other receiving sham tSCS, both combined with exoskeleton-assisted walking (EAW). It plans to enroll 24 participants.

What's involved

Participants will receive 60 minutes of exoskeleton-assisted walking (EAW) and transcutaneous spinal cord stimulation (tSCS) training per session, three times a week for 36 weeks, totaling 108 sessions. Muscle cross-sectional area will be measured at the start and after 9 months.

Compensation

Not stated in the trial record.

Follow-up

Participants will be assessed at enrollment (baseline) and again after 9 months of participating in the study interventions.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.