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MB-Spirit for Stress Reduction and Well-being

This study is testing two online programs, MB-Spirit and Strong Behaviors for Stress Reduction, to see if they can help adults aged 18 to 50 reduce stress and improve their spiritual well-being. You can join if you understand English, can attend all classes, and can travel to Boston for MRI scans (if selected for that part of the study). The main goal is to see if these programs improve your sense of meaning and peace after 8 weeks. The study is currently unclear on its recruitment status and plans to enroll 44 participants.

Study design
This is an interventional study where 44 participants with high stress will be randomly assigned to either a live online course or a self-paced program. A subset of participants will also have MRI scans before and after the program.
What's involved
You would participate in an 8-week online course (either live or self-paced), complete questionnaires and an interview before and after the course, and record daily homework practice. Some participants will also have MRI scans before and after their program.
Compensation
Not stated in the trial record.
Follow-up
Your spiritual well-being will be measured at 8 weeks after starting the program.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07325448

Assessing MB-Spirit for Psychological Well-being

Recruiting
NAAges 18–50Interventional
Sara W Lazar
~44 participants
Updated 2026-06-11 on ClinicalTrials.gov
What's tested:MB-SpiritStrong Behaviors for Stress Reduction

At a glance

Recruiting sites
1 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
FACIT-SP meaning and peace subscale
Measured over 8 weeks

Conditions

Stress

Explore related trials

Stress

Where it's being run

2 sites across 1 states
Massachusetts2

Study leadership

  • Sara Lazar, PhD · PRINCIPAL_INVESTIGATOR · Massachusetts General Hospital

Who to contact

Study Staff
[email protected]
617-415-8813
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Understands English
Able to attend all 8 classes
Able to travel to Boston for MRI scans

Exclusion

claustrophobia, pregnancy, head trauma, metallic implants or devices contraindicating MRI, left-handed, conditions that alter cerebral blood flow or metabolism (e.g. stroke), current use of psychotropic medications, lifetime history of suicidality, homicidally, self-destructive acts, schizophrenia or psychosis.

What this trial measures

  • FACIT-SP meaning and peace subscale8 weeks

    The meaning and peace subscale of the widely used and well-validated FACIT-SP-non-illness (Functional assessment of chronic illness therapy spiritual wellbeing - non illness) is our primary outcome metric. It has very good reliability (alpha=.81) and has high discriminate validity.