Remote Brain Stimulation and Training for TBI Recovery in Seniors

This study is exploring if combining brain stimulation (tDCS) with cognitive training can improve thinking skills in older adults (65+) who have experienced a mild traumatic brain injury (TBI). Researchers want to see if this combination helps with attention, memory, and decision-making, and if it's practical to do at home. You would receive either active tDCS (transcranial direct current stimulation) or a sham (placebo) version, along with computer-based cognitive training. The main goal is to measure changes in your thinking skills using a test called RBANS and brain activity using an EEG, at different times after the intervention. To join, you must be a veteran aged 65 or older with a history of mild TBI and self-reported attention or concentration difficulties.

Study design
This interventional study plans to enroll 40 participants, comparing two groups: one receiving active tDCS and cognitive training, and another receiving sham tDCS and cognitive training.
What's involved
You would complete 45 minutes of cognitive training, with brain stimulation for part of that time. Your thinking skills and brain activity will be measured at the start, one week after, and six weeks after the intervention.
Compensation
Not stated in the trial record.
Follow-up
Your progress will be followed for six weeks after the intervention ends.

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NCT07332299

Remote Stimulation and Training to Advance Recovery From TBI in Seniors

Recruiting
NAAges 65+InterventionalTreatment
Minneapolis Veterans Affairs Medical Center
~40 participants
Updated 2026-01-12 on ClinicalTrials.gov
What's tested:Active tDCS and Cognitive Training InterventionSham tDCS and Cognitive Training Intervention

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) Total Scale Score
Measured over Baseline, 1-week post, & 6-weeks post intervention
+1 more outcome measured
Traumatic Brain Injury
Aging Related Cognitive Decline
1 sites across 1 states
Minnesota1

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  • Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) Total Scale ScoreBaseline, 1-week post, & 6-weeks post intervention

    The RBANS is a commonly-used, psychometrically-sound measure of cognitive function across the lifespan. The primary outcome measure is the Total Scale score, which is a standard score (mean 100, SD 15) across five cognitive domains (Immediate/Delayed Memory, Visuospatial, Attention, Language).

  • Electroencephalogram (EEG) - Resting State Theta Band Functional ConnectivityBaseline, 1-week post, & 6-weeks post intervention

    Resting State EEG will be collected to assess neural dynamics or functional connectivity and spectral power of delta,theta, alpha, beta, and gamma frequency bands. The primary outcome measure will be change in prefrontal-parietal functional connectivity in the theta frequency band.