Evaluating Protein Loading on Kidney Function Measurement
This study aims to understand how protein intake affects the measurement of renal reserve (the kidney's ability to increase its filtering work) using a new device called the MediBeacon Transdermal Glomerular Filtration Rate (tGFR) Measurement System. You would receive an intravenous (IV) injection of Lumitrace and have the MediBeacon sensor placed on your chest. Researchers will then measure your estimated glomerular filtration rate (eGFR), which indicates how well your kidneys are filtering waste. The study is looking for 25 adult volunteers, aged 18 and older, who have an eGFR greater than 30 ml/min/1.73 m². The goal is to see if this system can accurately assess renal reserve, which is typically measured after a high-protein meal.
- Study design
- This is an interventional study planning to enroll 25 adult participants. The study will evaluate the effect of protein loading on kidney function measurement.
- What's involved
- You would receive an intravenous injection of Lumitrace and have a MediBeacon sensor attached to your chest. The primary measurement, renal reserve percentage, will be taken on Day 1.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary endpoint, renal reserve percentage, is measured at Day 1. Further follow-up information is not specified.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Evaluation of Protein Loading on Measurement of Renal Reserve
At a glance
Conditions
NCT07335614
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Fletcher Allen Health Care, University of Vermont Medical School
Burlington, Vermontno site contact published
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Richard B Dorshow, PhD · STUDY_DIRECTOR · MediBeacon, Inc.
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Renal reserve percentageDay 1
Renal reserve (%) will be calculated as Peak glomerular filtration rate (GFR) during the assessment period minus the average baseline GFR/average baseline GFR.