Phase 1 Study of SBS-147 for Pain

This study is testing a new drug called SBS-147 to see how safe it is and how your body handles it. Researchers are also looking for any side effects. You might receive SBS-147 or a placebo (a substance with no medicine) to help compare results fairly. This study is for healthy adults aged 18 to 55. The main goal is to understand what medical problems participants might have while taking SBS-147. Some participants will take SBS-147 or placebo once, while others will take it once or twice daily for 7 days. The study aims to enroll 80 participants.

Study design
This is an interventional study involving 80 healthy adult participants. Some will receive SBS-147, and others will receive a placebo.
What's involved
You would stay at the clinic for 5 days for the single-dose group, or 10 days for the multiple-dose group. This includes tests, blood draws, and questionnaires, with a final visit on Day 8 or Day 14.
Compensation
Not stated in the trial record.
Follow-up
Participants in the single-dose group will have an end-of-study visit on Day 8. Participants in the multiple-dose group will have an end-of-study visit on Day 14.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07335913

Phase 1 Study of SBS-147 in Healthy Adults

Recruiting
PHASE1Ages 18–55InterventionalTreatment
Sparian Biosciences, Inc
~80 participants
Updated 2026-03-03 on ClinicalTrials.gov
What's tested:SBS-147Placebo

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Number of participants with treatment-related adverse events as assessed by CTCAE v5.0
Measured over 8 days
+1 more outcome measured
Pain Acute
Pain
1 sites across 1 states
California1
  • Jeff Reich, MD · STUDY_DIRECTOR · Sparian Biosciences

Opens a ready-to-send draft in your own email app — review before sending.

  • Number of participants with treatment-related adverse events as assessed by CTCAE v5.08 days

    To assess the number of treatment emergent adverse events experienced in participants after a single dose of SBS-147

  • Number of participants with treatment-related adverse events as assessed by CTCAE v5.0 at ascending doses14 days

    Assess the number of treatment emergent adverse events experienced by participants of SBS-147 after multiple dose oral administration in healthy adults.