Digital Speech Markers for Monitoring ALS in Spanish Speakers

This observational study aims to understand how speech and breathing change over time in Spanish-speaking individuals with Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's Disease. Researchers want to see if measurements from a smartphone app can reliably track changes in speech and breathing related to ALS. You might be able to join if you are 18 to 90 years old, have a definite ALS diagnosis, speak Spanish as your first language, can read Spanish, and have a certain speech score on a common ALS scale. You cannot have certain lung conditions or currently use tobacco. The study will compare your speech and breathing with healthy individuals of similar age and gender to identify potential digital markers for ALS progression.

Study design
This is an observational study involving about 30 Spanish-speaking individuals with ALS and 5 healthy individuals. It is a prospective, longitudinal study, meaning participants will be followed over time.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint, oral speaking rate, will be measured from enrollment to 2-4 years.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07341334

Digital Speech Markers for Monitoring ALS in Spanish Speakers

Not Yet Recruiting
Not specifiedAges 18–90Observational
Nova Southeastern University
~35 participants
Updated 2026-08-03 on ClinicalTrials.gov

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Oral Speaking Rate
Measured over From enrollment to 2-4 years
Amyotrophic Lateral Sclerosis
Lou Gehrig's Disease
ALS

NCT07341334

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Cathy J Husman ALS Center at Nova Southeastern University

    Fort Lauderdale, Floridano site contact published

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Lauren Tabor Gray, Ph.D CCC-SLP · PRINCIPAL_INVESTIGATOR · Nova Southeastern University

Opens a ready-to-send draft in your own email app — review before sending.

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Eligibility criteria

Inclusion

diagnosis of definite ALS
monolingual or first language Spanish speaker
literate in Spanish
ALS Functional Rating Scale speech score of ≧2

Exclusion

no diagnosis of concomitant respiratory disease such as COPD, emphysema, or current TOB use.
  • Oral Speaking RateFrom enrollment to 2-4 years

    Speaking rate (words per minute): a measure of the rate of speech during oral reading.