Essential Amino Acid Supplementation for Adult Spinal Deformity

This study is looking at whether taking an Essential Amino Acid Supplement by Amino Co can help adults with spinal deformity recover better after corrective surgery. Researchers want to see if this supplement, given for two weeks before surgery and three months after, can improve how your body builds and repairs muscle compared to a placebo (an inactive substance). You might be able to join if you are between 40 and 65 years old, have adult spinal deformity, are scheduled for surgery at UAMS, live near Little Rock, and will attend physical therapy there. The main goal is to measure muscle protein synthesis (how your body makes new muscle) 24 hours after surgery. The current recruitment status is unclear.

Study design
This is a randomized, double-blind, placebo-controlled study, meaning participants will be randomly assigned to receive either the supplement or a placebo, and neither you nor the researchers will know which you are receiving. The study plans to enroll 20 participants.
What's involved
You would take the Essential Amino Acid Supplement by Amino Co (or placebo) twice a day for two weeks before surgery and then for 12 weeks after surgery.
Compensation
Not stated in the trial record.
Follow-up
Muscle protein synthesis will be measured at 24 hours after surgery, and supplementation continues for 12 weeks post-surgery.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07341399

Essential Amino Acid Supplementation in Adult Spinal Deformity Patients

Enrolling by Invitation
NAAges 40–65InterventionalSupportive care
University of Arkansas
~20 participants
Updated 2026-08-11 on ClinicalTrials.gov
What's tested:Essential Amino Acid Supplement by Amino CoPlacebo

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Muscle Protein Synthesis
Measured over 24 hours
Adult Spinal Deformity

NCT07341399

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • University of Arkansas for Medical Sciences

    Little Rock, Arkansasno site contact published

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Shiloah Kviatkovsky · PRINCIPAL_INVESTIGATOR · UAMS

This trial hasn't published a contact. View it on ClinicalTrials.gov

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Eligibility criteria

Inclusion

Males and Females, 40 to 65 years old
Diagnosed with adult spinal deformity
Scheduled for ASD corrective procedure at UAMS (\>2 weeks prior to surgery)
Live near Little Rock and scheduled to attend physical therapy in Little Rock
COVID-19 negative and/ or asymptomatic

Exclusion

Subject who does not/will not eat animal protein sources.
Diagnosed metabolic or hormonal disease (i.e., renal, cardiovascular, thyroid, polycystic ovary syndrome, or type I/II diabetes mellitus).
Currently pregnant.
Gave birth or was lactating within previous 12 months.
History of chemotherapy or radiation therapy for cancer in the 6 months prior to enrollment.
Clinically significant weight gain or loss (\>5% change) in the last 12 months.
Consuming metabolism-altering drugs or medications (i.e., corticosteroids, stimulants, insulin).
Diagnosis of autoimmune disease
Currently receiving androgen (e.g., testosterone) or anabolic (e.g., GH, IGF-I) therapy.
Diagnosis of muscular degenerative/dystrophy disease
Unwilling to fast overnight.
Unwilling to avoid using other protein or amino-acid supplements during participation.
  • Muscle Protein Synthesis24 hours

    Mixed muscle protein synthesis expressed as the fractional synthetic rate.