Cerebraca Wafer and Temozolomide for Recurrent Glioblastoma

This study is comparing two treatments for recurrent glioblastoma (a type of aggressive brain cancer that has returned): Cerebraca Wafer plus temozolomide versus temozolomide alone. Cerebraca Wafer is an implant used during surgery, and temozolomide is a standard chemotherapy drug. The study aims to see if adding Cerebraca Wafer improves how long people live. You might be able to join if you are 18 or older, have glioblastoma that has returned for the first or second time after initial treatment, and have completed prior surgery, temozolomide, and radiation. The study is looking for 175 participants. The current recruitment status is unclear.

Study design
This is a multi-center, randomized, open-label study, meaning participants are randomly assigned to a treatment group, and both you and your doctors will know which treatment you are receiving. It plans to enroll 175 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The main goal is to measure how long participants live, with this being assessed at 24 months.

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NCT07349693

Comparison of Cerebraca Wafer Plus Temozolomide Versus Temozolomide Alone in Recurrent Glioblastoma

Not Yet Recruiting
PHASE2Ages 18+InterventionalTreatment
Everfront Biotech Co., Ltd.
~175 participants
Updated 2026-01-20 on ClinicalTrials.gov
What's tested:Cerebraca waferTemozolomide (for relapsed malignant glioma)

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Median overall survival (OS)
Measured over 24 months
Recurrent Glioblastoma, IDH-Wildtype
1 sites across 1 states
Rhode Island1

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  • Median overall survival (OS)24 months

    Median overall survival (OS) in recurrent glioblastoma patients (event-based)