NCT07353918

Low-Intensity Focused Ultrasound Neuromodulation for Epilepsy

Enrolling by Invitation
NAAges 18–85InterventionalTreatment
Carilion Clinic
~6 participants
Updated 2026-01-21 on ClinicalTrials.gov
What's tested:Low-intensity Focused UltrasoundSham

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Seizure Frequency
Measured over 6 months past their final research study visit
Epilepsy (Treatment Refractory)
Epilepsy Comorbidities
1 sites across 1 states
Virginia1
  • Aashit Shah, MD · PRINCIPAL_INVESTIGATOR · Carilion Clinic

This trial hasn't published a contact. View it on ClinicalTrials.gov

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Eligibility criteria

Inclusion

Diagnosis of medically refractory focal epilepsy of mesial temporal onset
RNS system implantation in the hippocampus
Prior MRI and CT of the head
Able to consent for themselves
Internet access

Exclusion

TBI (ongoing, or in the prior 6 months)
Currently pregnant or breastfeeding
Progressive diseases - such as autoimmune epilepsies or diagnosis of a progressive neurological disorder
Status epilepticus within one year of study start
History of suicidal ideation or attempts in the last 6 months
  • Seizure Frequency6 months past their final research study visit

    Utilizing the implanted RNS system patient seizure frequency will be monitored over time following both real and sham intervention.