EA-230 for Hospital Stay After CABG Surgery

This Phase III clinical trial is testing a new treatment called EA-230 for people having coronary artery bypass graft (CABG) surgery. EA-230 is given through an IV for 4 hours during surgery. Researchers want to see if EA-230 can help patients recover faster and reduce the amount of time they need to stay in the hospital after surgery, compared to a placebo (an inactive treatment). Earlier research suggested EA-230 might shorten hospital stays and reduce complications. You may be able to join if you are at least 18 years old and scheduled for elective CABG surgery with at least 3 bypasses. This study is currently unclear on its recruitment status.

Study design
This is a Phase III, double-blind, randomized, placebo-controlled study involving 300 participants. Neither you nor your doctors will know if you receive EA-230 or a placebo.
What's involved
You would receive EA-230 or a placebo intravenously for 4 hours during your CABG surgery.
Compensation
Not stated in the trial record.
Follow-up
Your hospital length of stay will be measured for up to 28 days after surgery.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07357675

A Clinical Trial To Investigate The Effect Of EA-230 On Hospital Length Of Stay In Patients With Coronary Artery Disease (CAD) Undergoing Coronary Artery Bypass Grafting (CABG) Surgery.

Not Yet Recruiting
PHASE3Ages 18+InterventionalTreatment
EBI Anti Sepsis BV
~300 participants
Updated 2026-07-27 on ClinicalTrials.gov
What's tested:EA-230 90mg/kg/hourPlacebo

At a glance

Recruiting sites
0 of 6 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Required postoperative hospital length of stay
Measured over Up to 28 days
Coronary Artery Disease (CAD)
Coronary Artery Bypass Graft Surgery(CABG)
6 sites across 5 states
Netherlands2
Minnesota1
Pennsylvania1
Belgium1
United Kingdom1
  • Peter Pickers, Prof. · PRINCIPAL_INVESTIGATOR · Radboudmc

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  • Required postoperative hospital length of stayUp to 28 days

    Median postoperative duration, from the moment of first incision until the time when a patient is eligible to be discharged from the hospital.