Hyperbaric Oxygen Therapy for Fitness and Inflammation

This study is looking at whether Hyperbaric Oxygen Therapy (HBOT) can improve your cardiovascular fitness (VO₂ max) and reduce inflammation. HBOT involves breathing pure oxygen in a special pressurized chamber. We are looking for healthy adults between 30 and 60 years old who are physically active and haven't had HBOT recently. You cannot join if you have certain lung conditions or claustrophobia. The study will measure your inflammation levels (cytokines) and VO₂ max to see if HBOT is effective. This is an investigational use of HBOT, meaning it's still being studied for this purpose.

Study design
This interventional study plans to enroll 30 healthy adults. The specific phase of the study is not mentioned.
What's involved
You would receive 24 Hyperbaric Oxygen Therapy sessions, each lasting 100 minutes, three times a week for 8 weeks.
Compensation
Not stated in the trial record.
Follow-up
Your cytokine levels and VO₂ max will be measured up to 4 weeks after the end of treatment (12 weeks after your first treatment).

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NCT07361861

Evaluating Whether Hyperbaric Oxygen Therapy Can Improve VO₂-Max and Reduce Inflammation Markers in Healthy Adults Ages 30-60.

Recruiting
NAAges 30–60Interventional
University of Texas at Austin
~30 participants
Updated 2026-01-23 on ClinicalTrials.gov
What's tested:Hyperbaric Oxygen Therapy

At a glance

Recruiting sites
1 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Cytokine levels
Measured over From enrollment to 4 weeks after the end of treatment (12 weeks after first treatment).
+1 more outcome measured
Cardiovascular Fitness
Inflammation
2 sites across 1 states
Texas2

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

physically active individuals with no history of chronic illness or HBOT exposure within the last three months.

Exclusion

individuals with contraindications to HBOT, including lung diseases or claustrophobia.
  • Cytokine levelsFrom enrollment to 4 weeks after the end of treatment (12 weeks after first treatment).

    Cytokines will be measured via blood analysis. Samples will be taken before treatment, at the midpoint, at the end, and 4 weeks post treatment. This is a measure of inflammation in the body.

  • VO2 max testingFrom enrollment to 4 weeks post treatment (12 weeks after first treatment)

    A treadmill VO2 max test measured before treatment, at treatment midpoint, at the end of treatment, and 4 weeks after conclusion of treatment. This is an indicator of cardiovascular health.