Imaging the Colon Using a Colonoscope Compatible Imaging Probe

This study is testing a new device called a colonoscope compatible optical coherence tomography probe (CC-OCT probe). This probe is designed to take detailed images of your lower gastrointestinal (GI) tract during a standard colonoscopy. The main goal is to see if the CC-OCT probe is an effective tool for imaging the gut. You might be able to join if you are 45 years or older, can give informed consent, and can follow bowel preparation instructions. The study aims to enroll 250 participants, and success will be measured by the ability of the CC-OCT to capture images of the lower GI tract, which will be analyzed within one year.

Study design
This is an interventional study with 250 participants. All participants will receive the same intervention.
What's involved
During your standard colonoscopy, the CC-OCT probe will be inserted into the colonoscope to collect images of your gastrointestinal tract in real time.
Compensation
Not stated in the trial record.
Follow-up
Images are collected during the study procedure and analyzed within one year of collection.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07365436

Imaging the Colon Using a Colonoscope Compatible Imaging Probe

Enrolling by Invitation
NAAges 45–75Interventional
Massachusetts General Hospital
~250 participants
Updated 2026-07-13 on ClinicalTrials.gov
What's tested:Feasibility of using a CC-OCT probe to image the GI tract

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Ability of the CC-OCT to image the lower GI tract
Measured over Images are collected during the study procedure and analyzed within one year of collection
Colon Polyps
Colonoscopy
1 sites across 1 states
Massachusetts1
  • Guillermo Tearney, M.D., PhD · PRINCIPAL_INVESTIGATOR · Massachusetts General Hospital

This trial hasn't published a contact. View it on ClinicalTrials.gov

Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

45 years of age or older
Capable of giving informed consent
Capable of following bowel prep instructions

Exclusion

75 years of age or older
Any contraindication to bowel prep or colonoscopy
Current diagnosis of any bleeding disorders
Currently using drugs that interfere with coagulation (excluding low-dose aspirin)
Pregnancy
  • Ability of the CC-OCT to image the lower GI tractImages are collected during the study procedure and analyzed within one year of collection