Study of Butyrate + Polyphenol Formulation for Gut Health
This study is looking at how a special dietary supplement, called Butyrate + Polyphenol Formulation, affects gut health and related symptoms. You might be able to join if you are between 25 and 70 years old and have moderate to severe gastrointestinal (gut) symptoms. The researchers want to see if this formulation can improve your gut symptoms, as measured by a questionnaire, and change your gut microbiome (the community of tiny living things in your gut). Another group will receive a placebo, which looks like the supplement but has no active ingredients. The study aims to enroll up to 124 people.
- Study design
- This is a double-blind, randomized, placebo-controlled study, meaning neither you nor your doctor will know if you are receiving the active supplement or the placebo. Up to 124 participants will be enrolled.
- What's involved
- You will be asked to complete a laboratory assessment and questionnaires over a 14-day period. This will include a stool test to check your gut microbiome.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your gut health and symptoms will be measured at 14 days after starting the study.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
A Study to Evaluate the Effects of a Butyrate-Polyphenol Formulation on Gut Health and Associated Symptoms
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Andrew Swick, PhD · PRINCIPAL_INVESTIGATOR · Life Extension
Who to contact
This trial hasn't published a contact. View it on ClinicalTrials.gov
What this trial measures
- The Gastrointestinal Symptom Rating Scale (GSRS)-Irritable Bowel Syndrome (IBS) version14 days
Change in the Gastrointestinal Symptom Rating Scale-IBS from baseline. The responses to the questions range from no discomfort at all to very severe discomfort which would indicate a worse outcome
- Gut Microbiome Stool Test14 days
Change in the Gut Microbiome (strain level, functional metrics, taxonomy abundance and composition) from baseline