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Weight Management for Pediatric Leukemia Survivors

This study is looking at two different programs to help children who have had acute lymphoblastic leukemia (ALL) and their caregivers manage weight. You or your child might receive either educational materials from the National Institutes of Health (NIH) or a program called Modified Guided Self-Help Family Intervention (mL-GSH). The study is for children aged 6 to 18 who have been diagnosed with ALL and are currently receiving or recently finished maintenance chemotherapy. We want to see if these programs can help improve weight and body mass index (BMI) over about 12-15 months.

Study design
This is an interventional study with 80 participants. You and your caregiver will be randomly assigned to one of two groups.
What's involved
You will participate in six sessions over 6-9 months, and your weight and BMI will be measured at several points over 12-15 months. You will also wear a FitBit Ace to track physical activity.
Compensation
Not stated in the trial record.
Follow-up
Your weight and BMI will be measured for up to 6 months after the intervention ends, for a total study time of 12-15 months.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07374315

Weight Gain in Pediatric Leukemia Survivors

Not Yet Recruiting
NAAges 6+InterventionalPrevention
Washington University School of Medicine
~80 participants
Updated 2026-07-24 on ClinicalTrials.gov
What's tested:Modified Guided Self-Help Family InterventionNIH Educational ResourcesFitBit AceWashU Extended Learning Canvas

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Weight Z score
Measured over Enrollment, during intervention (4 months after enrollment), end of intervention (6 months after enrollment (may be up to 9 months)), and 6 months after end of intervention (estimated total time frame of 12-15 months)
+6 more outcomes measured

Conditions

Leukemia
Pediatric Acute Lymphoblastic Leukemia
Pediatric Acute Lymphoblastic Leukemia in Remission
Pediatric Obesity

Explore related trials

Acute Lymphoblastic Leukemia

NCT07374315

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Washington University School of Medicine

    St Louis, Missouristudy coordinator listed

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

  • Margaret Ferris, MD, PhD · PRINCIPAL_INVESTIGATOR · Washington University School of Medicine

Who to contact

Margaret Ferris, MD, PhD
[email protected]
314-454-6018
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

What this trial measures

  • Weight Z scoreEnrollment, during intervention (4 months after enrollment), end of intervention (6 months after enrollment (may be up to 9 months)), and 6 months after end of intervention (estimated total time frame of 12-15 months)

    Participant's weight Z score is a statistical value that indicates how the participant's weight for their age and sex compares to the average weight for that population which is obtained from Center for Disease Control (CDC) growth Charts

  • Changes in weight Z scoreFrom start of study through end of study (estimated total time frame 12-15 months)

    Participant's weight Z score is a statistical value that indicates how the participant's weight for their age and sex compares to the average weight for that population which is obtained from CDC growth Charts. Changes in weight Z score from start to end of the study will be analyzed by changes in summary statistics (mean, median, and standard deviation) across timepoints.

  • BMI Z ScoreEnrollment, during intervention (4 months after enrollment), end of intervention (6 months after enrollment (may be up to 9 months)), and 6 months after end of intervention (estimated total time frame of 12-15 months)

    Participant's BMI Z score is a statistical value that indicates how the participant's BMI for their age and sex compares to the average BMI for that population which is obtained from CDC growth Charts

  • Changes in BMI Z ScoreFrom start of study through end of study (estimated total time frame 12-15 months)

    Participant's BMI Z score is a statistical value that indicates how the participant's BMI for their age and sex compares to the average BMI for that population which is obtained from CDC growth Charts. Changes in BMI Z score from start to end of the study will be analyzed by changes summary statistics (mean, median, and standard deviation) across timepoints.

  • Changes in CholesterolEnrollment, during intervention (4 months after enrollment), end of intervention (6 months after enrollment (may be up to 9 months)), and 6 months after end of intervention (estimated total time frame of 12-15 months)

    Changes in cholesterol (total, LDL, and HDL levels) will be analyzed via summary statistics (means, medians, and standard deviation) at each of the endpoints.

  • Changes in HbA1cEnrollment, during intervention (4 months after enrollment), end of intervention (6 months after enrollment (may be up to 9 months)), and 6 months after end of intervention (estimated total time frame of 12-15 months)

    Changes in HbA1c will be analyzed via summary statistics (means, medians, and standard deviation) at each of the endpoints.

  • Changes in AlbuminEnrollment, during intervention (4 months after enrollment), end of intervention (6 months after enrollment (may be up to 9 months)), and 6 months after end of intervention (estimated total time frame of 12-15 months)

    Changes in albumin will be analyzed via summary statistics (means, medians, and standard deviation) at each of the endpoints.