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Music Therapy for Newly Diagnosed Glioblastoma (MELODY-GBM)

This study, called MELODY-GBM, is looking at whether music therapy can be helpful for people newly diagnosed with glioblastoma (GBM), a type of brain cancer. It's testing two types of music intervention: one where you have live virtual sessions with a music therapist twice a week for 8 weeks, and another where you get curated music playlists. The study aims to see how successful these music therapy interventions are for GBM patients, measured after 6 months. You might be able to join if you are 18 or older, have newly diagnosed GBM, can use a computer with internet, can attend virtual sessions, can hear music, and speak English. You also need to be planning to receive standard radiation and chemotherapy (temozolomide) and have a life expectancy of at least 6 months. The study is currently unclear on its recruitment status and plans to enroll 35 participants.

Study design
This interventional study will randomly assign participants into two groups. One group will have live virtual music therapy sessions, and the other will receive curated music playlists.
What's involved
Participants will engage in music interventions twice a week for 8 weeks and complete quality of life questionnaires. All interactions will be virtual via Zoom.
Compensation
Not stated in the trial record.
Follow-up
The primary outcome of the study, the success rate of music therapy, will be measured at 6 months.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07375992

Music Therapy in Newly Diagnosed Glioblastoma After Chemoradiation Therapy (MELODY-GBM)

Recruiting
NAAges 18+InterventionalTreatment
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
~35 participants
Updated 2026-06-18 on ClinicalTrials.gov
What's tested:Music intervention

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Success rate of Music Therapy intervention for GBM patients
Measured over 6 months

Conditions

Glioblastoma (GBM)

Explore related trials

Glioblastoma

Where it's being run

1 sites across 1 states
Maryland1

Study leadership

  • Matthias Holdhoff, MD, PhD. · PRINCIPAL_INVESTIGATOR · Johns Hopkins -Sidney Kimmel Cancer Center
  • Grace Tobin, MD · PRINCIPAL_INVESTIGATOR · Johns Hopkins University

Who to contact

Principal Investigator- Matthias Holdhoff, MD, PhD.
[email protected]
410-995-8837
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Glioblastoma (Newly Diagnosed)
Cognitive capacity to respond to surveys
Access to computer and web access
Ability to attend virtual music therapy sessions
Audibly process music
Proficient in English

Exclusion

Not planning to undergo standard of care radiation therapy and concurrent and adjuvant temozolomide.
A life expectancy of less than 6 months.
Concurrent use of any other standard or investigational agents (excepting tumor treating fields).
Uncontrolled intercurrent illness including, but not limited to, ongoing or active infection or psychiatric illness/social situations that would limit adherence with study requirements.

What this trial measures

  • Success rate of Music Therapy intervention for GBM patients6 months

    Determine success rate of the delivery of individualized virtual music therapy (MT) in participants undergoing standard of care treatment for newly diagnosed glioblastoma.