Botox with TURP or Aquablation for Mixed Urinary Symptoms

This study is looking at whether giving Onabotulinumtoxin A (Botox) at the same time as prostate surgery (Transurethral Resection of the Prostate or TURP, or Transurethral Waterjet Ablation of the Prostate or Aquablation) can help reduce bothersome urinary symptoms after surgery. These surgeries treat Benign Prostatic Hypertrophy (BPH), an enlarged prostate, but can sometimes cause symptoms like frequent or urgent urination. Botox is approved to treat overactive bladder. This study aims to see if combining Botox with these surgeries can make recovery smoother for men who experience both obstructive and overactive bladder symptoms. We are looking for about 20 men to participate. The study is currently unclear on its recruitment status.

Study design
This is an observational study, meaning researchers will collect information about your experience. It plans to include about 20 male participants.
What's involved
You would have a visit one week after surgery to check for urinary retention. At 4 and 12 weeks post-surgery, you would have a bladder scan and complete several questionnaires.
Compensation
Not stated in the trial record.
Follow-up
The primary goal is measured at 4 months after surgery, suggesting follow-up for at least that long.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07377929

Intradetrusor Onabotulinumtoxin A (Botox) at the Time of Transurethral Resection of the Prostate or Transurethral Waterjet Ablation of the Prostate for Mixed Lower Urinary Tract Symptoms

Recruiting
Not specifiedAges 18+Observational
Benaroya Research Institute
~20 participants
Updated 2026-01-30 on ClinicalTrials.gov
What's tested:Survey using a questionnaire.

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
To identify whether concurrent Botox and TURP or Aquablation are effective at reducing post-operative irritative voiding symptoms.
Measured over 4 months
Benign Prostatic Hypertrophy (BPH)
Lower Urinary Track Symptoms
1 sites across 1 states
Washington1

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  • To identify whether concurrent Botox and TURP or Aquablation are effective at reducing post-operative irritative voiding symptoms.4 months

    This will be measured using Postoperative Urinary Retention (POUR): At 1 week post-operative visit for trial of void to assess for rates of postoperative urinary retention. At 4 and 12 week post-operative visits for post void residual assessment