Rectus Abdominis Detrusor Myoplasty for Urinary Retention

This study is looking at a surgery called Rectus Abdominis Detrusor Myoplasty (RADM) for people with urinary retention, which means your bladder doesn't empty well. In this surgery, a part of your abdominal (belly) muscle is used to help your bladder squeeze and release urine. The study aims to see if this surgery improves how well your bladder works, specifically looking at bladder compliance (how much it can stretch), detrusor pressure (the pressure inside your bladder), and if detrusor overactivity (bladder muscle spasms) changes. You might be able to join if you are between 18 and 75 years old, have a bladder that doesn't contract well, and other treatments haven't worked. The study is currently unclear on its recruitment status and plans to enroll 50 participants.

Study design
This is an observational study looking at the outcomes of a specific surgery. It plans to include 50 participants.
What's involved
You would undergo the Rectus Abdominis Detrusor Myoplasty surgery. Your progress will be monitored for one year after the surgery.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 1 year after the surgery, with measurements taken at 6 months and 1 year.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07379814

Rectus Abdominis Detrusor Myoplasty for Urinary Retention

Recruiting
Not specifiedAges 18–75Observational
University Hospitals Cleveland Medical Center
~50 participants
Updated 2026-07-06 on ClinicalTrials.gov
What's tested:Rectus Abdominal Detrusor Myoplasty

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in Bladder Compliance
Measured over 6 Months and 1 Year Post-Op
+4 more outcomes measured
Urinary Retention
Urinary Retention After Procedure
Urinary Retention Postoperative
1 sites across 1 states
Ohio1
  • Shubham Gupta, MD · PRINCIPAL_INVESTIGATOR · University Hospitals Cleveland

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Eligibility criteria

Inclusion

Hypo- or acontractility of the bladder documented on urodynamic testing
Injury \>1 year ago for spinal cord injury patients, no improvement in contractility with time
Failed sacral nerve stimulation implant for urinary retention treatment (If previously implanted)
Irreversible non-neurogenic bladder acontractility/hypocontractility (i.e myogenic failure after chronic obstruction, aging, frailty, idiopathic)
Undergoing RADM

Exclusion

Documented bladder outlet obstruction
Spinal cord lesion above T12
Upper motor neuron lesion (i.e. multiple sclerosis, stroke)
Rectus diastasis, significant abdominal wall hernia, or other anatomic barrier to rectus flap harvest
Life expectancy \<10 years
Pregnant at time of surgery
  • Change in Bladder Compliance6 Months and 1 Year Post-Op

    Bladder compliance will be calculated as the change in bladder volume divided by the change in detrusor pressure during the filling phase and reported in milliliters per centimeter of water (mL/cm H₂O).

  • Change in Detrusor Pressure6 Months and 1 Year Post-Op

    Detrusor pressure during filling and voiding, including detrusor pressure at maximum flow, will be reported in centimeters of water (cm H₂O).

  • Change in presence of Detrusor Overactivity6 Months and 1 Year Post-Op

    Detrusor overactivity will be recorded as a binary variable (present or absent) based on the occurrence of involuntary detrusor contractions during filling.

  • Change in Urinary Flow Rate6 Months and 1 Year Post-Op

    Maximum urinary flow rate will be reported in milliliters per second (mL/s).

  • Change In Post-Void Residual Urine Volume in Urine6 Months and 1 Year Post-Op

    Post-void residual volume will be measured immediately following voiding and reported in milliliters (mL).