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Visual Influences on Vestibular Adaptation Study

This study is testing a balance-training exercise called Incremental Vestibulo-Ocular Reflex Adaptation (IVA) using a device called StableEyes. The goal is to see if IVA is safe and helps adults with vision problems, with or without additional inner-ear balance issues (vestibular hypofunction). Researchers want to know if IVA causes only mild side effects and if it improves eye-movement reflexes, balance, and walking. You might be able to join if you are between 18 and 60 years old and have abnormal vision, with or without vestibular hypofunction. The study is looking for 100 participants.

Study design
This is an interventional study with a planned enrollment of 100 participants. It compares different groups of people with vision problems, with or without balance issues.
What's involved
You will have at least two visits. During these visits, you will undergo the IVA intervention and have your Vestibulo-Ocular Reflex (VOR) gain measured.
Compensation
Not stated in the trial record.
Follow-up
Your VOR gain will be measured at baseline (before and after IVA) and again 2-10 days after baseline (before and after IVA).

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07380256

Visual Influences on Vestibular Adaptation

Recruiting
NAAges 18–60InterventionalBasic science
Emory University
~100 participants
Updated 2026-04-17 on ClinicalTrials.gov
What's tested:StableEyes: Incremental Vestibulo-Ocular Reflex Adaptation (IVA)

At a glance

Recruiting sites
1 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in Vestibulo-Ocular Reflex (VOR) Gain
Measured over Baseline (visit 1) (before and after after IVA intervention), Visit 2 (2-10 days from baseline) (before and after IVA intervention)

Conditions

Vestibular Hypofunction
Binocular Vision Abnormalities
Reduced Vision

Explore related trials

Abnormality of binocular visionLow VisionVestibulopathy

NCT07380256

Where you'd take part

This study runs at 2 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Dizziness and Balance Center

    Atlanta, Georgiastudy coordinator listed

    Recruiting

  • Emory Ophthalmology Clinics

    Atlanta, Georgiastudy coordinator listed

    Not yet recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

  • Colin Grove, PT, DPT, PhD · PRINCIPAL_INVESTIGATOR · Emory University

Who to contact

Colin R Grove, PT,DPT,PhD
[email protected]
(404) 712-8685
Email the study team

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Eligibility criteria

Inclusion

Age 18 to 60 years
Able to provide informed consent
Group 1: Abnormal Uncorrected Static Visual Acuity (No Vestibular Hypofunction) Normal peripheral vestibular function
Group 2: Abnormal Uncorrected Static Visual Acuity + peripheral Vestibular Hypofunction
Group 3: Binocular Vision Abnormalities (No Vestibular Hypofunction) Normal peripheral vestibular function
Group 4: Binocular Vision Abnormalities + peripheral Vestibular Hypofunction
Abnormal Static Visual Acuity: Uncorrected visual acuity (head is still) ≥0.30 logMAR in both eyes.
Unilateral Vestibular Hypofunction: 60 ms VOR gain \<0.80 unilaterally for the lateral semicircular canal.
Bilateral Vestibular Hypofunction: 60 ms VOR gain \<0.80 bilaterally for the lateral semicircular canals.
Normal Vestibular Function: 60 ms VOR gain of 0.80 to 1.20 bilaterally for the lateral semicircular canals.
Convergence Insufficiency: ≥6 cm near point of convergence.
Ocular Misalignment: ≥4 prism diopters of manifest deviation of the eyes (tropia) on cover/uncover testing.

Exclusion

Diagnosis of fluctuating vestibular disorders (e.g., benign paroxysmal positional vertigo)
Neurologic conditions (e.g., multiple sclerosis), dementia,
Alcohol or drug abuse,
A major psychiatric disorder (e.g., schizophrenia),
Pain that limits cervical spine range of motion by \>50% or that results in an -altered gait pattern.

What this trial measures

  • Change in Vestibulo-Ocular Reflex (VOR) GainBaseline (visit 1) (before and after after IVA intervention), Visit 2 (2-10 days from baseline) (before and after IVA intervention)

    VOR gain will be measured using the video head impulse test (vHIT). Gain is calculated as eye velocity divided by head velocity during high-acceleration, moderate velocity, small amplitude head rotations in the plane of the semicircular canals. This outcome quantifies the strength of the vestibulo-ocular reflex, with higher gain values indicating stronger VOR responses, with normal gain = 0.8 to 1.2. The change in VOR gain from before to after training will be used to assess VOR adaptation. IVA: Incremental Vestibulo-Ocular Reflex Adaptation