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RAMBO Registry for Knee Osteoarthritis

This observational study, called the RAMBO Registry, is looking at Genicular Artery Embolization (GAE) for adults with knee osteoarthritis (KOA). GAE is a procedure where tiny particles are used to block blood flow to certain arteries in the knee, aiming to reduce pain and inflammation. You might be able to join if you are 18 or older, have symptomatic KOA that hasn't improved with other treatments, and are referred for GAE. The study wants to see if GAE leads to lasting improvements in pain and quality of life over 12 to 36 months. They also want to understand what factors might lead to better results after GAE. The study aims to enroll 1200 participants, but its current recruitment status is unclear.

Study design
This is an observational study, also called a prospective registry, aiming to enroll 1200 participants. It collects real-world data on the effectiveness and safety of GAE.
What's involved
You would undergo GAE as part of your routine care and complete follow-up assessments at 1, 3, 6, 12, 18, 24, and 36 months, including questionnaires.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for up to 36 months after treatment to assess symptom and quality-of-life changes.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07380906

geniculaR Artery eMBolization for Knee Osteoarthritis (RAMBO) Registry

Recruiting
Not specifiedAges 18+Observational
Joint & Vascular Institute
~1,200 participants
Updated 2026-06-12 on ClinicalTrials.gov
What's tested:Genicular Artery Embolization

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)
Measured over 5 years of enrollment/patient

Conditions

Knee Osteoarthristis

Explore related trials

Osteoarthritis of knee

NCT07380906

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Joint and Vascular Institute

    Libertyville, Illinoisstudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Who to contact

Layth Alkhani
[email protected]
847-584-3959
Email the study team

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Eligibility criteria

Inclusion

Adults (≥18 years) with symptomatic KOA refractory to medical therapy, referred for GAE.

Exclusion

Pregnancy, coagulopathy, severe comorbidities, or inability to consent.

What this trial measures

  • Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)5 years of enrollment/patient

    The investigators will describe differences in pain response with Genicular Artery Embolization (GAE) compared to a sham procedure when treating medically refractory mild to moderate Knee Osteoarthritis (KOA) at 12 months as measured by the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Pain subscale score. A higher score index a higher pain level while a lower score indicates lower pain levels. The score range is 0 to 96.