This study is looking at how safe and effective a medication called tenapanor is for adults with Chronic Idiopathic Constipation (CIC). CIC is a type of long-lasting constipation without a known cause. You would receive tenapanor at one of three different doses (5 mg, 25 mg, or 50 mg, twice a day) or a placebo (a pill with no medicine). The main goal is to see if tenapanor helps you have regular, complete bowel movements. Adults aged 18 to 80 who meet specific criteria for functional constipation can join. The study status is currently unclear.

Study design

This is a 26-week, multi-center study where participants are randomly assigned to receive tenapanor or a placebo. It is double-blind, meaning neither you nor your doctors will know which treatment you are receiving. About 692 people are planned to join.

What's involved

You would have a 2-week screening period, followed by 26 weeks of treatment. During this time, you'll record your constipation symptoms daily in an electronic diary and attend clinic visits every 2 to 6 weeks.

Compensation

Not stated in the trial record.

Follow-up

After the 26-week treatment, there is a 4-week period where you will not take the study medication, but your safety will still be monitored.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.