Deceased Donor Kidney Storage at 10 Celsius Versus Conventional Storage

This study is looking at whether storing deceased donor kidneys at 10°C using the Traferox XPort device improves how well the kidney works after a transplant. Currently, kidneys are typically stored at 4°C (on ice). Researchers want to see if the warmer storage temperature leads to better kidney function. You could be eligible if you are an adult (18 years or older) on the kidney transplant waiting list at Vanderbilt University Medical Center. The main goal is to see if patients who receive a kidney stored at 10°C have better kidney function, measured by a urine test (Urine NGAL) the day after surgery. The study aims to enroll 30 participants, but its current recruitment status is unclear.

Study design
This interventional study plans to enroll 30 adult participants. It compares kidney function in patients receiving kidneys stored at 10°C versus those stored at 4°C.
What's involved
If you participate, you will receive a kidney transplant that was stored at 10°C. Your urine will be collected 24 hours after surgery for analysis.
Compensation
Not stated in the trial record.
Follow-up
Your kidney function will be assessed by a urine test collected the day after your kidney transplant.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07385651

Deceased Donor Kidney Storage at 10 Celsius Versus Conventional Storage

Recruiting
NAAges 18+InterventionalPrevention
Vanderbilt University Medical Center
~30 participants
Updated 2026-04-06 on ClinicalTrials.gov
What's tested:10˚C deceased donor kidney storage using Traferox XPort

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Urine NGAL
Measured over Urine collected post operatively day one after kidney transplant
End Stage Chronic Renal Failure
Chronic Kidney Disease (Stages 4 and 5)
Kidney Transplantation Recipients
1 sites across 1 states
Tennessee1
  • W. Christian Crannell, MD · PRINCIPAL_INVESTIGATOR · Vanderbilt University Medical Center

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  • Urine NGALUrine collected post operatively day one after kidney transplant

    Neutrophil gelatinase-associated lipocalin (NGAL), a urine biomarker for acute kidney injury that has been shown to be predictive of delayed kidney graft function. Urine will be collected after the kidney transplant, processed and stored with an anonymous ID.