Understanding Brain Function in Opioid Use

This study is looking at how guided meditation and psychoeducation (learning about how opioid use affects the brain) impact brain activity in people who use opioids or have opioid use disorder (OUD). Researchers want to see if these interventions change how brains work together (neurophysiological synchrony) and feelings of empathy. You might be able to join if you are 18 or older, use opioids almost daily, and can speak English. The study aims to enroll 60 participants and is currently unclear on its recruitment status. The main goal is to measure brain synchrony during and after the interventions.

Study design
This is an interventional study with 60 planned participants. It is not specified if it is randomized or blinded.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Neurophysiological synchrony will be measured during the intervention and for 5 minutes afterwards.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07386769

Interpersonal Brain Function in Opioid Use

Recruiting
NAAges 18+InterventionalBasic science
University of California, San Diego
~60 participants
Updated 2026-02-04 on ClinicalTrials.gov
What's tested:MeditationPsychoeducation

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Neurophysiological synchrony
Measured over During the intervention and for 5 minutes afterwards
People Who Use Opioids/People With Opioid Use Disorder (OUD)
1 sites across 1 states
California1
  • Eric Garland, PhD · PRINCIPAL_INVESTIGATOR · University of California, San Diego

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  • Neurophysiological synchronyDuring the intervention and for 5 minutes afterwards

    Dyadic Neural Synchrony (DNS) across electrodes and dyads will be computed from EEG oscillations using established inter-brain connectivity metrics. DNS will be quantified as a dyadic coupling parameter computed from time-series features extracted from each participant's EEG activity. Higher DNS values indicate greater therapist-patient neural attunement.