This study is testing if a mix of nitrous oxide and oxygen (Pro-Nox system) can reduce pain during in-office bladder Botox injections for conditions like overactive bladder or urge incontinence. You would receive your Botox injection and either use the Pro-Nox system with standard care (lidocaine in the bladder) or a sham mask with standard care. Researchers want to see if using nitrous oxide lowers your overall pain during the procedure. The study is currently unclear on its status and plans to enroll 96 adult women who are at least 18 years old and scheduled for this procedure. You cannot participate if you are pregnant or have certain health conditions like severe lung disease or vitamin B12 deficiency.

Study design

This is a randomized controlled trial comparing two groups: one receiving nitrous oxide/oxygen plus standard care, and another receiving a sham mask plus standard care. The study plans to enroll 96 participants.

What's involved

You would receive your bladder Botox injection in the office setting and answer brief questions about pain, anxiety, satisfaction, and willingness to repeat the procedure.

Compensation

Not stated in the trial record.

Follow-up

Overall pain will be measured at least 3 minutes after the procedure is completed.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.