Study of Weizmannia (Bacillus) coagulans JBI-YZ6.3 for Gut Health
This study is looking at how a dietary supplement called Weizmannia (Bacillus) coagulans JBI-YZ6.3 affects gut health and constipation in healthy, physically active adults. Researchers want to see if taking this probiotic daily for four weeks can improve constipation symptoms compared to a placebo (an inactive capsule). About 30 men and women between 18 and 50 years old will participate. You might be eligible if you experience daily bloating or bloating for more than 5 days in the past two weeks, and have a BMI between 18.5 and 29.9. The main goal is to measure changes in your constipation score.
- Study design
- This is a randomized, double-blind, placebo-controlled, crossover study involving about 30 participants. This means you will receive both the active supplement and a placebo at different times, and neither you nor the researchers will know which you are taking at any given time.
- What's involved
- You will take a capsule daily for two separate 4-week periods, with a 4-week break in between. The total study participation will be about 13 to 14 weeks, including screening and testing visits.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your constipation score will be measured at the beginning of the study and at the end of each 4-week supplementation period.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Impact of Weizmannia (Bacillus) Coagulans JBI-YZ6.3 on Gut Health and Fecal Microbiome Changes
At a glance
Conditions
NCT07388264
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Lindenwood University
Saint Charles, Missouristudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Chad M Kerksick, PhD · PRINCIPAL_INVESTIGATOR · Lindenwood University
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Constipation Score (Gastrointestinal Symptom Rating Scale)Baseline and end of each 4-week supplementation period (Weeks 0 and 4 of each intervention period)
Constipation will be assessed using the constipation domain of the Gastrointestinal Symptom Rating Scale (GSRS). The GSRS is a validated 15-item questionnaire scored on a 7-point Likert scale, where higher scores indicate greater symptom severity. The constipation domain includes items related to hard stools, constipation, and sensation of incomplete bowel emptying. Scores will be compared between the Weizmannia (Bacillus) coagulans JBI-YZ6.3 and placebo conditions.