NCT07388290
The Effect of Centralization on Medial Meniscal Extrusion for Medial Meniscus Posterior Root Tear Repair
Enrolling by Invitation
NAAges 18–65InterventionalTreatmentMayo ClinicInvestigator-initiated
~54 participants
Updated 2026-04-13 on ClinicalTrials.gov
What's tested:Medial meniscus posterior root tear (MMPRT) repair with meniscus centralizationMedial meniscus posterior root tear (MMPRT) repair without meniscus centralization
At a glance
Recruiting sites
0 of 3 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Meniscus extrusion measurement
Measured over Baseline (Preoperatively), 6 months
Conditions
Where it's being run
3 sites across 3 statesColorado1
Florida1
Minnesota1
Study leadership
- Aaron J. Krych, MD · PRINCIPAL_INVESTIGATOR · Mayo Clinic
Who to contact
This trial hasn't published a contact. View it on ClinicalTrials.gov
Do you actually qualify for this trial?
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Eligibility criteria
Inclusion
Type 2 Medial Meniscus Posterior Root Tear demonstrated on MRI
Notable extrusion (\>3 mm) on preoperative MRI
Patient able to consent for themselves
Patient agrees to comply with trial schedules and plan
Concomitant ligamentous or meniscal procedures
Meniscal extrusion \> 6 mm on pre-operative MRI
Kellgren-Lawrence grade \> 2
Varus malalignment \> 10 degrees
Asymmetric varus alignment \> 5 degrees
Varus thrust while weightbearing
Grade 3 bipolar medial compartment changes (isolated grade 3 changes on single articular surface with ≤ grade 2 changes on the opposing surface remains eligible)
Previous surgery of the affected knee
Associated fractures requiring surgery
Concurrent Vascular injuries
Hypermobility/Ehlers-Danlos Syndrome
Inflammatory or autoimmune disease
Severe mental/physical disability precluding post operative rehabilitation demands
Contraindications to MRI
Pregnant women
Complete radial tears within 9 mm of medial meniscus posterior root
ICRS Grade 3 or better
Exclusion
Requiring concomitant procedures other than MMPRT
ICRS Grade 4 changes
What this trial measures
- Meniscus extrusion measurementBaseline (Preoperatively), 6 months
Meniscus extrusion is measured in millimeters (mm) on coronal MRI at the level of the tibial spine