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Apple Cider Vinegar Supplementation for Kidney Stones

This study is looking at how taking Goli Apple Cider Vinegar gummies daily for two weeks affects your urine. Researchers want to see if it changes the levels of citrate, pH, and calcium in your urine. These changes are important because they can affect your risk of kidney stones. You might be able to join if you are an adult (18 or older) and have a history of calcium oxalate kidney stones, or if you are a healthy adult. You cannot join if you have certain other types of kidney stones or recent urinary tract issues. The study aims to enroll 30 people, but its current status is unclear.

Study design
This is a single-center study that will look at a group of participants. It plans to enroll 30 adults.
What's involved
You would take Goli Apple Cider Vinegar gummies daily for two weeks. Your urine chemistry will be measured at the start and after two weeks.
Compensation
Not stated in the trial record.
Follow-up
Your urine will be measured at the start of the study and again after two weeks.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07389226

The Effect of Apple Cider Vinegar Supplementation on 24-hour Urine Chemistry in Adults

Not Yet Recruiting
NAAges 18+InterventionalSupportive care
University of Chicago
~30 participants
Updated 2026-07-07 on ClinicalTrials.gov
What's tested:Apple Cider Vinegar

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Measure changes in citrate in urine.
Measured over From Enrollment to 2 weeks
+3 more outcomes measured

Conditions

Kidney Stones
Urine Specimen Collection

Explore related trials

Nephrolithiasis

Where it's being run

1 sites across 1 states
Illinois1

Study leadership

  • Luke Reynolds · PRINCIPAL_INVESTIGATOR · The University of Chicago Medical Center

Who to contact

Luke Reynolds
[email protected]
7137926105
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Controls: Adults above the age of 18.
Kidney stone patients: Adults above the age of 18.
History of majority (\>50%) calcium oxalate kidney stones

Exclusion

Anyone with a history of calcium phosphate stones (\>50% calcium phosphate), uric acid stones, struvite stones, recent urinary tract instrumentation (\<30 days), or recurrent urinary tract infections.
Any individual who has had ACV outside of normal consumption in the prior month will be excluded.
Any individual who has a history of a negative reaction (increased acid reflux, allergy) to ACV will also be excluded.
Any individual with chronic kidney disease, underlying acid base disorder will also be excluded.

What this trial measures

  • Measure changes in citrate in urine.From Enrollment to 2 weeks

    to evaluate the effect of short-term daily apple cider vinegar (ACV) supplementation on urine chemistry.

  • Measure changes in Urine PHFrom enrollment to 2 weeks

    to evaluate the effect of short-term daily apple cider vinegar (ACV) supplementation on urine chemistry.

  • Measure changes in calcium in urine.from enrollment to 2 weeks

    to evaluate the effect of short-term daily apple cider vinegar (ACV) supplementation on urine chemistry.

  • Measure changes in calcium oxalate in urineFrom Enrollment to 2 weeks

    to evaluate the effect of short-term daily apple cider vinegar (ACV) supplementation on urine chemistry.