NCT07393503
Musculoskeletal Outcomes Using Tylenol/Ibuprofen vs. Oral Steroids in New Injuries
Enrolling by Invitation
PHASE4Ages 18+InterventionalState University of New York at BuffaloInvestigator-initiated
~60 participants
Updated 2026-02-18 on ClinicalTrials.gov
What's tested:Methylprednisolone 4Mg TabAcetaminophen 500Mg TabIbuprofen 200Mg Oral Tablet
At a glance
Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in Pain
Measured over 1 week, 1 month
Conditions
Where it's being run
1 sites across 1 statesNew York1
Who to contact
This trial hasn't published a contact. View it on ClinicalTrials.gov
Do you actually qualify for this trial?
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Eligibility criteria
Inclusion
Adults 18+
Able to answer survey questions in English
MSK pain \> 3 on the VAS scale in any body part
Invited to participate by and enrolling clinician
Exclusion
\> 2 weeks from pain onset
Fractures
Active infections
Anaphylactic reaction to either medication (Oral Steroids, Ibuprofen, and/or Acetaminophen)
Currently taking anti-platelet agents (aspirin \</= 100/mg a day, clopidogrel, etc.)
Chronic Kidney Disease Stage 3 or worse
Uncontrolled diabetes (A1C above 9)
Currently taking oral anti-coagulants
History of bleeding ulcer
Cirrhosis
Taking daily prednisone
Chronic pain syndrome
Chronic pain medication (gabapentin, Lyrica, narcotics, etc.)
Pregnant Patients
Worker's Compensation Patients
What this trial measures
- Change in Pain1 week, 1 month
Pain as self-reported by the patient, following pain medication treatment for an acute musculoskeletal (MSK) injury as measured with the Visual Analog Scale (VAS) where 0 is no pain at all and 10 is the worst pain imaginable. Lower scores indicate less pain.