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NCT07397897

Intracranial EEG to Test How Noninvasive Stimulation Affects Hippocampal-dependent Memory

Enrolling by Invitation
NAAges 18+InterventionalBasic science
University of Chicago
~12 participants
Updated 2026-02-09 on ClinicalTrials.gov
What's tested:Transcranial magnetic stimulation (TMS)

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Power of theta-band hippocampal electroencephalography (iEEG) activity
Measured over Measured while research activities are being completed, including during stimulation and the performance of the task . Measurement will take 2 to 4 hours on a single day.
+1 more outcome measured

Conditions

Memory Performance
Hippocampal Network Activity

Explore related trials

Memory Disorders

Where it's being run

1 sites across 1 states
Illinois1

Study leadership

  • Joel Voss, PhD · PRINCIPAL_INVESTIGATOR · University of Chicago

Who to contact

This trial hasn't published a contact. View it on ClinicalTrials.gov

Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Age 18+ years old
Native English speakers
Normal or corrected-to-normal near and far vision

Exclusion

iEEG electrode placement in area of parietal lobe that will interfere with placement of TMS coil for HITS stimulation

What this trial measures

  • Power of theta-band hippocampal electroencephalography (iEEG) activityMeasured while research activities are being completed, including during stimulation and the performance of the task . Measurement will take 2 to 4 hours on a single day.

    Power of theta-band hippocampal iEEG activity will be recorded and used to measure local brain electrical activity evoked by task conditions

  • Electroencephalography (iEEG) activity between hippocampus and the stimulated electrodeMeasured while research activities are being completed, including during stimulation and the performance of the task . Measurement will take 2 to 4 hours on a single day.

    iEEG is used to measure local brain electrical activity evoked by task conditions. iEEG will be recorded and analyzed to determine the synchrony of iEEG activity between hippocampus and the stimulated electrode.