Simplified, Scalable, 24-hour Adaptive DBS for Parkinson's Disease
This study is testing a new way to treat Parkinson's disease (PD) using a deep brain stimulation (DBS) device called Medtronic Percept. You would have this device implanted, and it uses electrodes placed under your scalp. Researchers want to see if a personalized, adaptive DBS (aDBS) setting, which changes based on your brain signals, works better than the standard continuous DBS (cDBS) for managing your movement and/or sleep problems. They will compare how well aDBS works against cDBS. This study is looking for 24 participants between 25 and 75 years old who have idiopathic PD and haven't found enough relief from oral medications. The study's success will be measured by how much your bothersome movement and/or sleep episodes change with aDBS compared to cDBS.
- Study design
- This interventional study plans to enroll 24 participants. It will compare adaptive deep brain stimulation (aDBS) settings to continuous deep brain stimulation (cDBS) settings.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary outcome will be measured at Baseline, during aDBS testing, and during Blinded Assessment.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Simplified, Scalable, 24-hour Adaptive DBS in Parkinson's Disease
At a glance
Conditions
NCT07398157
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
University of California San Francisco
San Francisco, Californiastudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Simon Little · PRINCIPAL_INVESTIGATOR · University of California, San Francisco
- Philip Starr · PRINCIPAL_INVESTIGATOR · University of California, San Francisco
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Change in number of bothersome movement and/or sleep episodes on adaptive deep brain stimulation compared to open-loop deep brain stimulationBaseline, aDBS testing, and during Blinded Assessment
Troublesome movement and/or sleep episodes will be detected using validated home wearable devices along with participant self-reporting.