Motion Management for Lung Cancer Radiation

This study is testing a new way to track lung tumors and nearby organs during radiation treatment for non-small cell lung cancer (NSCLC). It uses a special MRI scan (4D CT Simulation and 4S MRI with surface monitoring) before radiation and X-ray images (fluoroscopy) during daily treatment. The goal is to see if this method can more accurately pinpoint the tumor and healthy organs compared to current standard methods. This study is for adults aged 18 and older with Stage II-IIIb NSCLC who are having radiation therapy. The study is currently unclear on its recruitment status.

Study design
This interventional study plans to enroll 44 participants. It is not specified if it is randomized or blinded.
What's involved
Participants will have a 4D CT Simulation and 4S MRI scan with surface monitoring before radiation, followed by fluoroscopy and additional surface monitoring during daily radiation.
Compensation
Not stated in the trial record.
Follow-up
The primary outcome will be measured at 3 years after the intervention.

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NCT07398209

GCC 2546- Motion Management

Recruiting
NAAges 18+InterventionalSupportive care
University of Maryland, Baltimore
~44 participants
Updated 2026-06-26 on ClinicalTrials.gov
What's tested:MRI

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
To investigate if time-resolved, multicycle volumetric motion modeling and monitoring gives improved spatiotemporal localization of the tumor target and OARs compared to current standard-of-care 4DCT-based motion modeling and monitoring
Measured over 3 years
Lung Cancer (NSCLC)
Radiation
1 sites across 1 states
Maryland1
  • Amit Sawant, PhD · PRINCIPAL_INVESTIGATOR · University of Maryland, Baltimore

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  • To investigate if time-resolved, multicycle volumetric motion modeling and monitoring gives improved spatiotemporal localization of the tumor target and OARs compared to current standard-of-care 4DCT-based motion modeling and monitoring3 years