Evaluating a Hepatitis C and HIV Screening Tool in the Emergency Department

This observational study is looking at different ways to screen for Hepatitis C (HCV) and HIV in the emergency department (ED). Researchers are comparing standard screening by doctors, a universal screening approach called FOCUS where nurses ask about testing, and a new tool called HepC-EnD. HepC-EnD uses a computer program to identify patients at high risk for HCV when they arrive at the ED. The goal is to see if these screening methods can help find more people with HCV or HIV who might not know they have it. You might be able to participate if you are between 18 and 79 years old and are not medically unstable. The study aims to measure the number of new HCV or HIV diagnoses before and after these screening methods are put in place.

Study design
This is an observational study with a planned enrollment of 6466 participants. It is comparing three different screening approaches for Hepatitis C and HIV.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The study measures outcomes for 6 months before and 6 months after the screening methods are implemented.

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NCT07406490

Assessing Performance of a Hepatitis C Emergency Department (HepC-EnD) Screening Tool: IT Integration Process for Electronic Health Record System

Not Yet Recruiting
Not specifiedAges 18–79Observational
University of Florida
~6,466 participants
Updated 2026-04-29 on ClinicalTrials.gov
What's tested:Physician-Initiated Screening (Conventional Screening)FOCUS (Universal Screening)HepC-EnD (Targeted Screening)

At a glance

Recruiting sites
0 of 3 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Proportion of new HCV or HIV diagnoses
Measured over Time Frame: 6 months pre- and post-implementation
+1 more outcome measured
Hepatitis C Virus (HCV)
Hepatitis C Virus (HCV) Infection
HIV (Human Immunodeficiency Virus)
3 sites across 1 states
Florida3
  • Haesuk Park, PhD · PRINCIPAL_INVESTIGATOR · University of Florida

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Eligibility criteria

Inclusion

18-79 years of age

Exclusion

\< 18 years of age
Medically unstable
  • Proportion of new HCV or HIV diagnosesTime Frame: 6 months pre- and post-implementation

    Proportion of positive results among performed tests. HCV diagnosis is defined as a positive RNA test result. HIV diagnosis is defined as an acute (i.e., antigen positive but antibody negative) or established (i.e., antibody positive) infection.

  • Absolute number of new HCV or HIV diagnoses6 months pre- and post-implementation

    Absolute number of positive results among performed tests. HCV diagnosis is defined as a positive RNA test result. HIV diagnosis is defined as an acute (i.e., antigen positive but antibody negative) or established (i.e., antibody positive) infection.