Comparing Direct vs. Standard Laser Treatment for Glaucoma
This study is comparing two FDA-approved laser treatments for glaucoma: Direct Selective Laser Trabeculoplasty (DSLT) and Selective Laser Trabeculoplasty (SLT). Both procedures aim to lower the pressure inside your eye (intraocular pressure or IOP) to help prevent vision loss caused by open-angle glaucoma or ocular hypertension (high eye pressure). DSLT is a newer, non-contact method that might be more comfortable and efficient. You would be randomly assigned to receive either DSLT or SLT. Researchers will follow your eye pressure and safety for 12 months to see how well each treatment works. The study plans to enroll 172 participants. To join, you must be at least 18 years old with open-angle glaucoma or ocular hypertension, and have an open angle in your eye. You cannot participate if you have angle-closure glaucoma, very high eye pressure (over 35 mmHg) despite treatment, or had recent eye surgery.
- Study design
- This is an interventional study comparing two laser treatments. Participants will be randomly assigned to receive either Direct Selective Laser Trabeculoplasty (DSLT) or Selective Laser Trabeculoplasty (SLT). The study plans to enroll 172 participants.
- What's involved
- Participants will receive one of two laser treatments and have their eye pressure and safety monitored for 12 months.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for 12 months after treatment to assess changes in intraocular pressure.
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Direct vs Standard SLT for Glaucoma: A Noninferiority Trial
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Jella An, MD · PRINCIPAL_INVESTIGATOR · Medical University of South Carolina
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Change in Intraocular Pressure at 12 months from baseline12 months