Study of BMS-986528 for Refractory Rheumatoid Arthritis

This study is testing a drug called BMS-986528 in people with rheumatoid arthritis (RA) that is difficult to treat. The main goals are to understand how safe BMS-986528 is and how well your body handles it. Researchers will also look for early signs that the drug might help improve RA. You could join if you are an adult between 18 and 65 years old with difficult-to-treat RA. The study aims to enroll 84 participants. The current recruitment status is unclear.

Study design
This is an interventional study, meaning participants will receive a specific treatment. It plans to enroll 84 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for safety events for up to 54 weeks after treatment.

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NCT07412704

A Study of BMS-986528 in Participants With Refractory Rheumatoid Arthritis

Recruiting
PHASE1Ages 18–65InterventionalTreatment
Bristol-Myers Squibb
~84 participants
Updated 2026-08-24 on ClinicalTrials.gov
What's tested:BMS-986528

At a glance

Recruiting sites
3 of 39 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Number of participants with treatment-emergent adverse events (TEAEs)
Measured over Up to Week 54
+1 more outcome measured
Arthritis, Rheumatoid
39 sites across 30 states
Germany4
California3
Colorado2
New York2
Shanghai Municipality2
Switzerland2
Florida1
Oregon1
  • Bristol-Myers Squibb · STUDY_DIRECTOR · Bristol-Myers Squibb
BMS Clinical Trials Contact Center www.BMSClinicalTrials.com
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Eligibility criteria

Exclusion

Juvenile arthritis or onset of inflammatory arthritis before age 18.
Seronegative RA participants in whom polymyalgia rheumatica has not been ruled out.
Active fibromyalgia with pain symptoms or signs that would interfere with joint assessment.
  • Number of participants with treatment-emergent adverse events (TEAEs)Up to Week 54
  • Number of participants with Serious Adverse Events (SAEs)Up to Week 54