HELIOS Advanced: Photobiomodulation for IVF Outcomes
This study, called HELIOS Advanced, is looking at a gentle light treatment called photobiomodulation (PBM) during in vitro fertilization (IVF). PBM uses a special type of red or near-infrared light to help the "power plants" of your cells (mitochondria) work better. As women get older, these power plants don't work as well, which can make it harder for eggs and embryos to develop. Researchers want to see if PBM can improve embryo growth. You may be able to join if you are a woman between 18 and 48 years old, are undergoing IVF with your own eggs, and plan to have blastocyst culture. The main goal is to see how many usable blastocysts (developed embryos) are created seven days after egg retrieval. The current status of this study is unclear.
- Study design
- This is an interventional study with a planned enrollment of 270 women. It involves comparing oocytes that receive photobiomodulation to those that do not.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary endpoint, number of usable blastocysts, is measured seven days after egg retrieval. Participants also plan to transfer euploid embryos within six months.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
HELIOS Advanced: Human Oocyte Illumination to Enhance Development
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Samuel Zev Williams, MD/PhD · PRINCIPAL_INVESTIGATOR · Columbia University
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Number of usable blastocystsSeven days post egg retrieval
Usable blastocysts are defined as blastocysts that can be biopsied and frozen on Day 5, 6, or 7 of development for PGT-A (pre-implantation genetic testing for aneuploidy). The study will calculate the usable blastocyst rate per oocyte retrieved defined as the number of usable blastocysts divided by the number of oocytes retrieved.