Nurse-Led PTSD Treatment in Primary Care

This study is testing a new program called NurseNET for people with Post Traumatic Stress Disorder (PTSD) who have also recently experienced a life-threatening heart event. PTSD is a serious condition, and this study aims to see if specially trained nurses can provide effective, short-term treatment directly in primary care clinics. This could make it easier for more people to get the help they need, as there aren't always enough mental health specialists available. The study will compare NurseNET to standard referral for PTSD treatment. Researchers will measure changes in your PTSD symptoms using a questionnaire called the PCL-5 over 12 months to see how well NurseNET works.

Study design
This study is an interventional trial planning to enroll 100 participants. It compares a nurse-led treatment called NurseNET with standard referral to PTSD treatment.
What's involved
You would have your PTSD symptoms measured at the start of the study, and then again at 3, 6, and 12 months.
Compensation
Not stated in the trial record.
Follow-up
Your PTSD symptoms will be followed for 12 months after starting the study.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07430657

Nurse-Led PTSD Treatment in Primary Care

Recruiting
NAAges 18+InterventionalTreatment
Rush University Medical Center
~100 participants
Updated 2026-04-29 on ClinicalTrials.gov
What's tested:NurseNETReferral to PTSD Treatment

At a glance

Recruiting sites
2 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
PTSD Checklist for DSM-5 (PCL-5)
Measured over Baseline, 3, 6, 12 months
Post Traumatic Stress Disorder PTSD
2 sites across 2 states
Illinois1
Wisconsin1
Kirsten Dickins Assistant Professor, PhD
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

o PTSD + trauma exposure (PCL-5 score ≥28, plus trauma endorsed on LEC-5/CAPS)
Life-threatening CV event in the last 90 days (including myocardial infarction/heart attack, acute cerebrovascular accident/stroke, sudden cardiac arrest, acute decompensated heart failure, or life-threatening arrhythmia requiring cardioversion or defibrillation).
Primary care patient at Rush University Medical Center

Exclusion

o Safety risk (documented suicidal ideation/need for acute psychiatric care)
NET conflict (actively receiving psychotherapy/PTSD treatment)
Cognitive/decisional non-capacity (University of California, San Diego Brief Assessment of Capacity to Consent \[UBACC\] ≤ 14.5)
  • PTSD Checklist for DSM-5 (PCL-5)Baseline, 3, 6, 12 months

    20-item self-report scale that assesses the 20 DSM-5 PTSD symptoms; used to monitor symptom change/screen for probable PTSD diagnosis.