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Observational Study on Essential Tremor Stigma and Tremor Suppression

This observational study is looking at how a procedure called stereotactic thalamotomy with focused ultrasound affects the feelings of stigma and social difficulties experienced by people with Essential Tremor (ET). ET causes involuntary shaking, which can lead to people feeling misunderstood or judged. The study wants to see if reducing tremor with this procedure can also reduce the psychological distress and social problems related to ET stigma. You might be able to join if you have ET diagnosed by a specialist, your tremor is severe enough to consider brain surgery, and you can consent to the focused ultrasound procedure. The study is currently unclear on its status and plans to enroll 220 participants.

Study design
This is an observational study that plans to enroll 220 participants. It is not specified if it is randomized or blinded.
What's involved
You would complete three short surveys before the thalamotomy procedure and again 12 months later. Each time, the surveys take about 5 minutes to complete.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 12 months after the stereotactic thalamotomy procedure.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07430761

ET Stigma Response to Tremor Suppression

Recruiting
Not specifiedAges 18+Observational
University of Texas Southwestern Medical Center
~220 participants
Updated 2026-02-24 on ClinicalTrials.gov
What's tested:stereotactic thalamotomy with focused ultrasound

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
ET stigma psychological distress
Measured over change from baseline before thalamotomy to 12 months after thalamotomy
+1 more outcome measured

Conditions

Action Tremor
Stigma, Social

Explore related trials

Essential Tremor

Where it's being run

1 sites across 1 states
Texas1

Study leadership

  • Padraig E O'Suilleabhain, MD · PRINCIPAL_INVESTIGATOR · University of Texas Southwestern Medical Center

Who to contact

Padraig E O'Suilleabhain, MD
[email protected]
2146482943
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

People with ET as diagnosed by a movement disorder neurologist
Tremor of sufficient severity and impact on quality of life so as to justify a lesional brain procedure
Competent to consent to undergoing high intensity focused ultrasound thalamotomy targeted by 4-tract tractography
Provide verbal informed consent to this study of ET stigma

Exclusion

Patient declines to participate in this observational study

What this trial measures

  • ET stigma psychological distresschange from baseline before thalamotomy to 12 months after thalamotomy

    Psychological distress related to other people's reaction to their tremor.

  • ET stigma social dysfunctionchange from baseline before thalamotomy to 12 months after thalamotomy

    Social avoidance and maladaptive behaviors related to other people's reaction to tremor.