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Personalized AI-Driven Models in Cognitive Behavioral Therapy for Anxiety

This study is looking at how personalized AI (artificial intelligence) models can improve Cognitive Behavioral Therapy (CBT) for college students with Generalized Anxiety Disorder (GAD). CBT is a type of talk therapy. The study will test two types of personalized CBT using a Socially Assistive Robot (SAR) for 6 weeks: one where the personalization is clearly defined (Explicit CBT SAR Personalization) and another where it's based on machine learning (Implicit CBT SAR Personalization). There's also a control group using a non-personalized SAR. The goal is to see if these personalized robots help students stick with their daily CBT exercises. You can join if you are a university student, 18 or older, speak English, and have mild to elevated anxiety symptoms (a GAD-7 score of 5 or higher). The study will measure how much you interact with the robot and how many days you complete your exercises. The current recruitment status is unclear.

Study design
This is an interventional study with 140 planned participants. You would be randomly assigned to one of three groups: two personalized CBT SAR groups or a control group with a non-personalized SAR.
What's involved
You would engage in 6 weeks of daily in-home CBT exercises with a Socially Assistive Robot. You would also have an initial in-home visit to receive the robot and instructions.
Compensation
Not stated in the trial record.
Follow-up
The primary measurements for this study will be taken throughout the 6-week study period.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07430800

Personalized AI-Driven Models in Cognitive Behavioral Therapy for Anxiety

Recruiting
NAAges 18+InterventionalBasic science
University of Southern California
~140 participants
Updated 2026-06-08 on ClinicalTrials.gov
What's tested:Explicit CBT SAR Personalization for 6 weeksImplicit CBT SAR Personalization for 6 weeksControl CBT SAR for 6 weeks

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Number of user-spoken words during interactions with SAR
Measured over During each session, through study completion, approximately 6 weeks.
+6 more outcomes measured

Conditions

Generalized Anxiety Disorder (GAD)

Explore related trials

Generalized Anxiety Disorder

Where it's being run

1 sites across 1 states
California1

Who to contact

Lydia Ignatova
[email protected]
714-855-7076
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Are 18 years of age or older
Are university students
Are able to communicate in English
Have corrected-to-normal vision and hearing
Consent to have audio/video/interaction data recorded as part of the study
Have a GAD-7 (Generalized Anxiety Disorder-7 item) score of 5 or greater, indicating mild to elevated levels of self-reported symptoms of anxiety
Have a lower than minimal level of suicidality risk as measured by the Columbia Suicide Severity Rating Scale (C-SSRS) during screening ("NO" responses to items 3, 4, 5, and 6 on C-SSRS)
Having access to home WiFi

Exclusion

Are less than 18 years of age
Are not university students
Are not able to communicate in English
Do not have corrected-to-normal vision and hearing
Do not consent to have audio/video/interaction data recorded as part of the study
Have a GAD-7 (Generalized Anxiety Disorder-7 item) score of 4 or lower.
Higher than a minimal level of suicidality risk as measured by the Columbia Suicide Severity Rating Scale (C-SSRS) during screening ("YES" responses to items 3, 4, 5, or 6 on C-SSRS)
Don't have access to home WiFi

What this trial measures

  • Number of user-spoken words during interactions with SARDuring each session, through study completion, approximately 6 weeks.

    Using transcriptions of the interactions, the investigators will count the number of words uttered by the participant.

  • Overall length of interaction sessionsThrough the duration of the study, approximately 6 weeks.

    Using the interaction data from the robot interface, the investigators will collect the time that the participant started the interaction with the robot and the time that the interaction ended.

  • Number of days participants complete CBT exercises (adherence)Through study completion, approximately 6 weeks.

    Using the interaction data from the robot interface, the investigators will collect the number of days that the participant interacts with the system at least once during the day

  • Outcomes Questionnaire-45.2Once in weeks 1, 3, 6 of the study.

    The total reported symptom distress value from the symptom distress subscale. Question scale (0-4). A higher total score indicates higher distress overall, and higher scores for question subsets indicate worse outcomes for symptom distress, interpersonal relations, and social role.

  • Modified Working Alliance Inventory-Short RevisedOnce in weeks 2, 4, 6 of study.

    Repeated daily measure for assessing the quality of the relationship with the SAR companion. Question scale (1-5). Higher scores indicate stronger alliance.

  • Sustem Usability ScaleOnce on Week 2 Day 4 and Week 6 Day 4.

    The total reported usability score for evaluating participant perception of SAR companion's usability. Question responses scale from strongly agree to strongly disagree. Responses should not indicate trends in participant outcomes, but should instead help the investigators understand participants' perception of the system.

  • Semi-structured interviewOne interview for 30 minutes - 120 minutes at the end of the 6 week study.

    Focus group interviews with the investigators and participants will be used to process for collecting qualitative feedback and insights. The investigators will use this data to perform thematic analysis of participant responses while using the system.